Yuchao Jiang

Yuchao Jiang is a member at the Lineberger Comprehensive Cancer Center and an Assistant Professor in the Department of Biostatistics and the Department of Genetics. Jiang’s lab focuses on genetic and genomic research.

Assistant Professor
UNC-Chapel Hill
Department of Biostatistics
Department of Genetics
Lineberger Comprehensive Cancer Center

Area of interest

Yuchao Jiang has conducted research in developing statistical methods and computational algorithms to: (i) detect germline and somatic copy number variation and estimate allele-specific copy number by next-generation sequencing under various experimental designs with and without negative controls; (ii) assess intratumor heterogeneity and reconstruct tumor phylogeny by multi-regional and/or longitudinal DNA sequencing of bulk tumor specimens; and (iii) model allele-specific gene expression and characterize allele-specific bursting by single-cell RNA sequencing with adjustment of technical variability. While his research is focused on method development, he has also worked closely with biologists, geneticists, and oncologists and applied statistical methods to large-scale cohort studies of human health and diseases to better utilize and analyze different types of next-generation sequencing data.

Awards and Honors

  • 2018 UNC Lineberger Developmental Award
  • 2017 Saul Winegrad Award for Outstanding Dissertation, University of Pennsylvania
  • 2016 President Gutmann Leadership Award, University of Pennsylvania
  • 2015 Best Pre-Doc Poster, Symposium on Advances in Genomics, Epidemiology and Statistic


Find publications on PubMed