Victoria Bae-Jump, MD, PhD

Professor and Fellowship Director, Division of Gynecologic Oncology

Research Interests

• Impact of obesity on ovarian and endometrial cancer pathogenesis and treatment.
• Inter-relationship of obesity and the microbiome underlying racial disparities in endometrial cancer.
• Novel therapeutics for ovarian and endometrial cancer.

Russell Broaddus, MD, PhD

Joe W. and Evelyn M. Grisham Distinguished Professor
Chair of Pathology and Laboratory Medicine

Research Interests

• Molecular pathogenesis of endometrial cancer.
• Developing molecular diagnostics for predicting endometrial cancer histotype, stage, and recurrence developing clinical and lab-based algorithms for the identification of patients with hereditary endometrial cancer.
• Discovering novel molecular mediators of endometrial cancer invasion and metastasis.
• Identifying novel signaling pathways important in the pathogenesis of endometrial cancer.

Ian Davis, MD, PhD

G. Denman Hammond Professor for Childhood Cancer, Departments of Pediatrics and Genetics

Research Interests

• Clinical pediatric oncology.
• Relationship between chromatin and transcriptional regulation in pediatric cancers.
• Computational and experimental approaches to study the impact of mutations in chromatin regulatory genes on cancer development.
• Discovery of epigenetic strategies to treat cancer.

Gianpietro Dotti, MD, PhD

Professor, Microbiology and Immunology

Research Interests

• CAR-T cell therapy
• Treatment of malignancies using gene modified T lymphocytes.
• Development of chimeric antigen receptors, transgenic T-cell receptor, cytokine and cytokine receptor expressions from preclinical assessment to clinical application
• Development of countermeasure to the tumor immunosuppressive environment.

H. Shelton Earp, MD

Director, UNC Lineberger Comprehensive Cancer Center
Director, UNC Cancer Care
Distinguished Professor of Medicine

Research Interests

• Breast Cancer.
• Receptor tyrosine kinases.
• Tumor Microenvironment
• Innate Immunity
• Translational Research

Yuri Fedoriw, MD

Co-Director, UNC Project-Malawi Cancer Program, Global Cancer Pathology Director, Institute for Global Health and Infectious Diseases

Research Interests

• Immunologic and genetic mechanisms of lymphomagenesis, particularly in the setting of HIV infection.
• Advanced sequencing, immunophenotypic and cellular analyses to address gaps.
• Understanding of lymphomagenesis and tumor microenvironment in the context of HIV-associated immune dysregulation.

Shawn Gomez, PhD

Academic Director and Associate Professor, Biomedical Engineering
Associate Professor, Pharmacology

Research Interests

• Computational Biology
• Systems Biology
• Informatics
• Cancer

Gaorav Gupta, MD, PhD

Assistant Professor, Departments of Radiation Oncology and Biochemistry and Biophysics

Research Interests

• To understand the interplay between genome integrity pathways and breast cancer initiation, progression, and response to therapy.

William Kim, MD

Rush S. Dickson Distinguished Professor of Medicine
Professor of Genetics

Research Interests

• Genetic and epigenetic events involved in the initiation and progression of renal cell carcinoma (RCC) and bladder cancer.
• NextGen sequencing of primary human tumors, genetically engineered mouse models, in vitro systems.

Yueh Lee, MD, PhD

Associate Professor, Radiology
Adjunct Assistant Professor, Physics and Astronomy and Biomedical Engineering

Research Interests

• Translational Medical Imaging Research & First-in-human Imaging studies.
• Contrast enhanced ultrasound, CNT X-ray sources, 19F MRI, PET/MRI and neuro-oncology.

Zibo Li, PhD

Associate Professor, Radiology

Research Interests

• Novel molecular imaging probes.
• Techniques for non-invasive detection of cancer.
• Molecular imaging.

Chad Pecot, MD

Associate Professor of Medicine, Hematology/Oncology

Research Interests

• Medical oncology, specializing in lung and triple-negative breast cancers.
• Solid tumor malignancies.
• How RNA interference can regulate cancer metastases and be used for novel therapeutics.

Charles Perou, PhD

Professor of Genetics
Co-Director, Computational Medicine

Research Interests

• Breast cancer genomics
• Computational medicine
• Gene expression profiling

Yuliya Pylayeva-Gupta, PhD

Assistant Professor, Genetics

Research Interests

• Investigation of mechanisms used by tumors to co-opt the immune system to facilitate emergence/progression of cancer.
• Biology of pancreatic cancer.
• Genetically engineered mouse models of pancreatic cancer.

Jonathan Serody, MD

Elizabeth Thomas Professor of Medicine, Microbiology and Immunology
Associate Director for Translational Science, UNC-Lineberger Comprehensive Cancer Center
Co-leader, Immunology Program, UNC Lineberger Comprehensive Cancer Center

Research Interests

• Translational Research.
• Breast Cancer.
• Tumor and transplant immunology.
• Tumor microenvironment in solid tumors.

Jen Jen Yeh, MD

Professor, Departments of Surgery and Pharmacology
Vice Chair for Research, Department of Surgery

Research Interests

• Role of tumor and stroma molecular subtypes.
• Study of novel therapeutic targets and identification of novel therapies in pancreatic cancer.
• Patient-derived models of pancreatic cancer.