Scientists implicate genes behind faulty DNA repair in breast cancer

September 20, 2019

While mutations in BRCA genes are well known to increase breast cancer risk, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have uncovered a different series of genes they believe might be contributing to breast cancer through a lesser-known mechanism. Mutations in BRCA cause cells to lose the ability to repair errors … Continued

Susan G. Komen awards nearly $1.5M in breast cancer research grants to UNC Lineberger

September 16, 2019

Susan G. Komen® today announced it was providing $1.45 million in research grants to three UNC Lineberger Comprehensive Cancer Center members as part of a national campaign focused on metastatic breast cancer, developing new, more-effective treatments, and addressing disparities in breast cancer outcomes. The grants support Komen’s commitment to achieve its Bold Goal to reduce … Continued

Researchers identify strategy to block immunosupressive signals in melanoma

September 16, 2019

Cancer cells have a clever approach to avoid key immune cells intent on killing them. Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center report in the journal Cancer Immunology Research they have developed a strategy to shut down signals that keep cancer-killing immune cells from infiltrating melanoma. By blocking receptors on the … Continued

Researchers develop method for identifying aggressive breast cancer drivers

August 13, 2019

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method to precisely identify individual … Continued

Muss leads study published in Journal of Clinical Oncology

August 13, 2019

UNC Lineberger’s Hyman B. Muss, MD, the Mary Jones Hudson Distinguished Professor in the UNC School of Medicine Division of Hematology/Oncology and director of UNC Lineberger’s geriatric oncology program, led a study published in the Journal of Clinical Oncology that found that older patients with early breast cancer had lower rate of recurrence when treated … Continued

Major gift supports efforts in breast cancer research

June 24, 2019

Bill and Nancy Graham of Winston-Salem, North Carolina, have donated $1 million to support breast cancer research and care at the UNC Lineberger Comprehensive Cancer Center. The Grahams established the Bill and Nancy Graham Breast Cancer Research Fund to provide the cancer center’s leadership with unrestricted funding, which enables them to make investments where the … Continued

Researchers identify traits linked to better outcomes in HPV-linked head and neck cancer

June 13, 2019

Using a new blood test that’s in development, University of North Carolina Lineberger Comprehensive Cancer Center researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection. Researchers believe the findings, published in the journal Clinical Cancer Research, could help identify those … Continued

Carey recognized as fellow of the American Society of Clinical Oncology

June 3, 2019

Lisa A. Carey, MD, FASCO, was named a fellow of the American Society of Clinical Oncology during its annual meeting in Chicago, May 31-June 4. The distinction recognizes ASCO members for their extraordinary volunteer service, dedication, and commitment to the organization, which represents nearly 45,000 oncology professionals who care for people living with cancer. Carey, … Continued