PSC Services
The Pathology Services Core may offer additional services not listed here. For more information, contact us by telephone at 919-445-4179 or by e-mail at gdelacruz@med.unc.edu.
For Clinical Trials:
Please fill out the form below and attach it in ilabs when submitting a clinical trial related request:
Clinical_Trial_Request_Form_UNC_LCCC_w_instructions_20220831
Tissue Processing
Pull slides or blocks from UNCH archive
Tissue/cell line processing and embedding
FFPE tissue sectioning and coring
RNase free FFPE tissue sectioning and coring
De-Calcification
Tissue Micro Array (TMA)
TMA and Cell Line Array (CLA) design
TMA and CLA construction
TMA/CLA sectioning
Histochemical Stains
H&E
Special Stains:
| Acid Fast Bacillus (AFB) | Bielschowsky | Carmine | Colloidal Iron | Congo Red |
| Cresyl Violet | DAPI | Fites Stain | Giemsa | Melanin Bleach |
| Methylene Blue | Periodic Acid Schiff (PAS) | Prussian Blue | Phosphotungstic Acid Hematoxylin (PTAH) | Rhodamine Copper |
| Safranin O | Schmorl | Sirius Red | Sudan Black | Von Kossa |
| Alcian Blue | Alcian Blue – PAS | Brown & Brenn | Fontana Masson | Grocott’s Methenamine Silver (GMS) |
| Luxol Fast Blue (LFB) | LFB-PAS | Martius Scarlet Blue | Mayer’s Mucicarmine | Masson Trichrome |
| Oil Red O | Pico-Sirius Red | Reticulin | Sudan Black | Verhoeff-Van Gieson (VVG) |
| Jones Basement Membrane | Steiner | Warthin Starry |
IHC, IF and ISH
Automated IHC-single
Automated IF –double and triple
Automated IF –UltivueTM four marker multiplex
ISH (RNA) Chromogenic w/ Leica probes
ISH (RNA) chromogenic (single) or IF (single and multiplex) w/ RNAscope probes
NEW* – GeoMXTM Digital Spatial Profiler – up to 96 antibodies or 1000 RNA targets per slide
Whole Slide Scanning and Image Storage
Aperio ScanScope AT2, bright field
Aperio ScanScope FL, immunofluorescence
Versa, bright field and immunofluorescence
Aperio eSlide Manager, centralized image storage
Image Analysis (Aperio Toolbox and Genie, Definiens Tissue Studio, Visiopharm)
Tissue composition analysis
Cellular analysis
Image alignment (e.g. IF slide aligned with corresponding H&E for analysis)
Pathology
Pathology (MD) review for clinical trials