PSC Services
The Pathology Services Core may offer additional services not listed here. For more information, contact us by email at gdelacruz@med.unc.edu.
For Clinical Trials: Please fill out the form below and attach it in iLabs when submitting a clinical trial related request.
Services
Project Management
- Clinical trial coordination
- Study design consultation and coordination
- Antibody and methodology consultation
- Multi-Core pipeline coordination
Tissue Processing
- Tissue/cell line processing and embedding
- De-Calcification
- FFPE tissue sectioning and coring
- RNase free FFPE tissue sectioning and coring
- Frozen sectioning
- Pull slides or blocks from UNCH archive
- Visium (10x Genomics) specialized sectioning
Tissue Micro Array (TMA)
- TMA and Cell Line Array (CLA) design
- TMA and CLA construction
- TMA/CLA sectioning
Histochemical Stains
- H&E
- Special Stains
- Special stains and immunostaining multiplexing
Immunostaining
- Automated Immunohistochemistry (IHC) – Single and Dual
- Automated Immunofluorescence (IF)
- Automated in situ hybridization (ISH/FISH)
Spatial Profiling
- GeoMx DSP, NanoString
- Phenocycler, Akoya
- Visium and Visium CytAssist, 10x Genomics
- RNAscope, Advanced Cell Diagnostics
- miRNAscope, Advanced Cell Diagnostics
- BaseScope, Advanced Cell Diagnostics
Whole Slide Scanning and Image Storage
- Aperio ScanScope AT2, bright field
- Aperio ScanScope FL, immunofluorescence
- Versa, bright field and immunofluorescence
- Aperio eSlide Manager, centralized image storage
Image Analysis (Aperio Toolbox and Genie, Definiens Tissue Studio, Visiopharm)
- Tissue composition analysis
- Cellular analysis
- Area Quantification
- Object Identification
- Pattern Recognition
- Image alignment (e.g. IF slide aligned with corresponding H&E for analysis)
- NEW: HistoQC analysis
Pathology
- Pathology (MD) review for clinical trials
- Pathology (DVM) consultation and review