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Chuck Perou, PhD (left) presents at the 6th Annual Princess Noorah Oncology Center International Breast Cancer Conference

October 28, 2014

UNC Lineberger researchers present at international breast cancer conference in Saudi Arabia

Three UNC Lineberger members - Lisa Carey, MD, medical director of the UNC Breast Center, division chief of hematology and oncology at the UNC School of Medicine, and physician-in-chief of the N.C. Cancer Hospital, Matt Ewend, MD, Van L. Weatherspoon Jr. Distinguished Professor of Neurosurgery and chair of the UNC Department of Neurosurgery, and Chuck Perou, PhD, professor of genetics and pathology – served as speakers at the 6th Annual Princess Noorah Oncology Center International Breast Cancer Conference held in Jeddah.

August 24, 2014

UNC Lineberger researchers develop new approach to identify “drivers” of cancer

UNC Lineberger Comprehensive Cancer Center researchers have developed a new integrated approach to pinpoint the genetic “drivers” of cancer, uncovering eight genes that could be viable for targeted breast cancer therapy. The study, published online August 24 in Nature Genetics, was authored by Michael Gatza, PhD, lead author and post-doctoral research associate; Grace Silva, graduate student; Joel Parker, PhD, director of bioinformatics, UNC Lineberger; Cheng Fan, research associate; and senior author Chuck Perou, PhD, professor of genetics and pathology.

July 1, 2014

Study in mice finds weight loss reduces progression of basal-like breast cancer

Obesity, epidemic in the U.S. and worldwide, is one of the important modifiable risk factors for breast cancer, especially a particularly aggressive subtype called basal-like breast cancer (BBC). Population studies have suggested that lifestyle interventions, including weight loss, could prevent a large proportion of this type of cancer; however, data on the effect of weight loss on BBC risk are limited and the mechanisms involved uncertain.