September 6, 2019
Vaping may harm fertility in young women
E-cigarette usage may impair fertility and pregnancy outcomes, according to a study Kathleen Caron, PhD, and colleagues published in the Journal of the Endocrine Society.
Tag: Cancer Cell Biology Research Program
August 26, 2019
HealthDay News: Vaping May Trigger Lung Damage Like That Seen in Emphysema
August 22, 2019
E-cigs can trigger same lung changes seen in smokers, emphysema
E-cigarette “vaping” is widely assumed to be safer than cigarette smoking, but scientists at the University of North Carolina have uncovered evidence suggesting that vaping promotes the same cellular responses found in smokers with emphysema. In a study published in the American Journal of Respiratory and Critical Care Medicine, the UNC scientists found that the lungs of vapers …
April 19, 2019
Study provides insights behind hyperactivation of key cell proliferation signal
The idea was simple: find the faulty signals that drive cancerous growth in cells, and block them. But what University of North Carolina Lineberger Comprehensive Cancer Center researcher Pengda Liu, PhD, has discovered, when it comes to cancer, even straightforward concepts can become complicated. “When you find a target and inhibit it, you find the …
March 12, 2019
Scientists discover key enzyme in breast cancer proliferation, treatment resistance
Basal-like breast cancer is the most aggressive and difficult-to-treat subtype of breast cancer, and it largely overlaps with the triple-negative classification of the disease. Patients are in dire need of improved therapies that attack the underlying cellular features of these types of breast cancer. Now scientists at the University of North Carolina Lineberger Comprehensive Cancer …
February 11, 2019
UNC Lineberger awards $1.35M for cancer research
UNC Lineberger awarded grants to 14 scientists and research teams in the fall grant awards cycle. Applications for the next round of funding will be due March 15.
January 31, 2019
Scientists uncover mechanism cells use to deactivate a signal that’s hyperactive in cancer
University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have discovered how a cellular signal that’s abnormally hyperactive in cancer can be deactivated. In the journal Cell Reports, UNC Lineberger’s M. Ben Major, PhD, and colleagues published a paper on how the WNT signaling pathway is regulated. WNT proteins increase tumor onset, growth …
January 29, 2019
Researchers publish milestone review on the role of cell signaling proteins in cancer
University of North Carolina Lineberger Comprehensive Cancer Center scientist Antonio “Tony” Amelio, PhD, is not necessarily looking for the “smoking gun” of cancer biology, or one single cause of cancer. Instead, he’s looking into how a family of newly described proteins involved in the cellular stress response can cause a complex ripple effect of changes …
October 5, 2018
Insights about prostate cancer resistance could lead to treatment strategies
In the journal Molecular Cell, researchers led by UNC Lineberger's G. Greg Wang, PhD, and H. Shelton Earp, MD, describe the role of a protein variant called androgen receptor variant 7 (AR-V7), which is an alternative form of the androgen receptor that plays a key role in prostate cancer development and treatment.
July 19, 2018
Discovery of kidney cancer driver could lead to new treatment strategy
In a study published in the journal Science, researchers led by UNC Lineberger's Qing Zhang, PhD, suggest that ZHX2 is a potential new therapeutic target for clear cell renal cell carcinoma, which is the most common type of kidney cancer.