Past Research to Practice Webinars

Dana Casey, MD

Assistant Professor
Radiation Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Matthew Foster, MD

Associate Professor of Medicine
Division of Hematology
Leukemia, Lymphoma, and Myeloma Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Speaker TBD,

UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Anne W. Beaven, MD

Associate Professor of Medicine
Vice Chief of Operations, Division of Hematology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Gita Mody, MD, MPH

Director of Thoracic Surgical Oncology
Assistant Professor of Surgery
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Yara Abdou, MD

Assistant Professor
Division of Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Yara Abdou, MD, from the UNC Lineberger Breast Oncology group will describe relevant updates in systemic therapy for breast cancers for health care providers throughout the state of North Carolina.

Webinar Objectives:

• • • Discuss recent advances in neoadjuvant and adjuvant systemic therapy approaches for patients with early-stage breast cancer.
    • Discuss recent advances in systemic therapy for patients with advanced stage or metastatic breast cancer.
    • Discuss the recent use of immunotherapy and targeted therapy in the management of breast cancer.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Natalie Grover, MD

Assistant Professor of Medicine
Division of Hematology
Clinical Director, Cellular Therapy Program
Co-Director, Urologic Oncology Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Faith Brianne Buchanan, PA-C

Physician Assistant, UNC Bone Marrow Transplant and Cellular Therapy Program
Division of Hematology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

CAR-T therapy is expanding as a therapeutic option both in clinical trials and FDA approved commercial products for cancer patients. This Webinar will review the current treatments and their use in patients with hematologic malignancies.

Webinar Objectives:

• • • Describe the currently available and new indications of FDA approved CAR-T products
    • Discuss current trends in side effect management and patient care considerations
    • Discuss future directions of CAR-T therapy in commercial and trial products, including active trials at UNC

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Matthew I. Milowsky, MD

The George Gabriel and Frances Gable Villere Distinguished Professor of Bladder and Genitourinary Cancer Research
Cancer Research
Section Chief, Genitourinary Oncology
Co-Director, Urologic Oncology Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Genitourinary malignancies will account for approximately 20% of newly diagnosed cancers in 2021. Recent research advances in prostate, bladder, and kidney cancers utilizing new biomarkers and imaging tools, radiolabeled therapy, targeted therapy, immunotherapy and antibody-drug conjugates have led to new management approaches associated with significant improvements in patient outcomes.

Webinar Objectives:

• • • Describe new PSMA-directed approaches in the imaging and management of patients with prostate cancer.
    • Review recent advances in systemic therapy for patients with muscle-invasive and metastatic bladder cancer.
    • Discuss the use of immunotherapy and targeted therapy approaches in the management of advanced kidney cancer.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Stephen Kimani, MD, MSc

Fellow
Division of Hematology/Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

This Webinar will provide an overview of the burden and outcomes of COVID-19 among patients living with cancer. We will also review the impact of the pandemic on cancer care delivery, and emerging data regarding vaccination safety and efficacy.

Webinar Objectives:

• • • Describe prevalence, incidence, and outcomes of COVID-19 among select populations of cancer patients in the US.
    • Compare safety and efficacy of available COVID-19 vaccines.
    • Discuss the impact of COVID-19 on cancer care delivery with emphasis on unique challenges and opportunities in oncology.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Alice Ma, MD, FACP

The Medical Alumni Loyalty Fund Distinguished Teaching Professor
Director, Division of Hematology Fellowship
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Immune Thrombocytopenic Purpura and Thrombotic Thrombocytopenic Purpura are both autoimmune conditions leading to low platelets, though the mechanism by which the platelets are consumed differs. The Webinar will update viewers on new therapies for the treatment of ITP and TTP

Webinar Objectives:

• • • Explain the role of thrombopoietin receptor agonists in the treatment of ITP.
    • Discuss the role of caplacizumab in the treatment of TTP.
    • Describe the optimal prophylaxis and immunizations for patients treated with prolonged corticosteroids or other immunosuppressants for ITP and TTP.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Wendell Yarbrough, MD, MMHC, FACS

Chair, Department of Otolaryngology/Head and Neck Surgery
Thomas J. Dark Distinguished Professor of Otolaryngology/Head and Neck Surgery
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Wendell Yarbrough, MD, MMHC, FACS, will Webinar on multi-disciplinary treatment of head and neck cancer with updates regarding new techniques and treatment standards. This Webinar will also give the audience updates on HPV-Associated Head and Neck Cancer with emerging therapeutic vulnerabilities.

Webinar Objectives:

• • • Discuss multi-disciplinary treatment of Head and Neck Cancer with emphasis on newer techniques and treatment standards.
    • Explain reconstruction techniques of Head and Neck Cancer.
    • Identify HPV-Associated Head and Neck Cancer, prognostic markers and emerging therapeutic vulnerabilities.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Emily Olsson, CCRP

Program Manager
Research Recruitment and Retention
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Alicia Bilheimer, MPH

Administrative Director
Community and Stakeholder Engagement Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

This Webinar is an interactive presentation and discussion to consider barriers to cancer clinical trial enrollment in North Carolina and potential approaches to address this. Topics will include the importance of patient and provider engagement, education and resources for identifying research opportunities and available trials, barriers and mitigation strategies to address population disparities in trial enrollment, and other issues. This session aims to provide information and strategies on participant recruitment, allowing individual study teams and/or clinicians from across the state to determine how research best fits into their individual models and how to present research participation as an option to all patients.

Webinar Objectives:

• • • Explain the importance of the clinician to patient awareness and acceptance of clinical trial participation.
    • Describe the trial recruitment process.
    • Identify feasible engagement strategies for non-research clinicians to incorporate into practice.
    • Identify resources for connecting patients to research education or trial opportunities.
    • Distinguish possible strategies to mitigate the diversity disparity in research.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Christopher Dittus, DO, MPH

Assistant Professor
Clinical Research, Hematology/Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Christopher Dittus from the UNC Lineberger Lymphoma group will describe relevant updates in systemic therapy for rare lymphomas for health care providers throughout the state of North Carolina. Additional topical management considerations or recommendations for this patient population may also be presented.

Webinar Objectives:

• • • Explain the diagnosis of mantle cell lymphoma.
    • Describe high risk mantle cell lymphoma.
    • Describe the frontline treatment approach for mantle cell lymphoma.
    • Describe new modalities for treating relapsed mantle cell lymphoma.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Benyam Muluneh, PharmD, BCOP, CPP

Clinical Assistant Professor
UNC Eshelman School of Pharmacy
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Benyam Muluneh from the UNC Eshelman School of Pharmacy will discuss relevant topics in cancer pharmacy for North Carolina cancer providers, such as adherence to oral anti-cancer therapies, evolving pharmaceutical practice models (e.g. specialized clinics), toxicity measurement and management, access, and other issues.

Webinar Objectives:

• • • Identify key practice-related barriers to optimal patient outcomes in oncology.
    • Differentiate patient-level and system-level challenges to delivering cancer care.
    • Describe best practices to enhance patient engagement, medication access, and treatment adherence.

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Emily Ray, MD, MPH

Associate Professor
Department of Anesthesiology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. James from the UNC Anesthesiology Department in affiliation with UNC Lineberger cancer treatment group, will describe effects of regional and neuraxial perioperative blocks on cancer outcomes. Additional topical management considerations or recommendations for this patient population may also be presented.

Webinar Objectives:

• • • Discuss effects of perioperative stress on cellular function and cancer outcomes.
    • Describe effects of general anesthesia on cancer outcomes.
    • Discuss the effects of neuraxial analgesia on cancer recurrence and mortality as pertaining to various malignancies .

Handouts

• • • 2-Up Handout
    • 3-Up Handout

Shetal A. Patel, MD, PhD

Assistant Professor
Clinical Research
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Shetal Patel, MD, PhD, from the UNC Lineberger Thoracic Oncology group will describe relevant updates in systemic therapy for lung cancers for health care providers throughout the state of North Carolina. Additional topical management considerations or recommendations for this patient population may also be presented.

Webinar Objectives

• • • Recognize biomarkers for targeted therapy selection for patients with non-small cell lung cancer.
    • Compare immune checkpoint inhibitor treatment options for metastatic non-small cell lung cancer.
    • Describe the role of immune checkpoint inhibitors in small cell lung cancer.

Emily Ray, MD, MPH

Assistant Professor
Department of Medicine
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Emily Ray, from the UNC Lineberger Breast Oncology group, will describe relevant updates in systemic therapy for breast cancers for health care providers throughout the state of North Carolina.

Webinar Objectives

• • • Recognize the options for adjuvant therapy in early stage HER2+ breast cancer
    • Describe the role of genomic assays in determining adjuvant treatment for early stage hormone receptor-positive (HR+) breast cancer
    • Define the options for treating metastatic HER2+ breast cancer

Trevor Royce, MD, MPH

Assistant Professor
Genitourinary Cancers, Clinical Research
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Trevor Royce from the UNC Lineberger Department of Radiation Oncology will describe relevant updates in radiation oncology for health care providers throughout the state of North Carolina. With a focus on bladder cancer—highlights will include updates on techniques and indications for radiotherapy, toxicity monitoring, recent research, and other issues.

Webinar Objectives

• • • Describe the role radiation can play in the multidisciplinary management of bladder cancer
    • Compare the roles of radiation and surgery in the treatment of muscle invasive bladder cancer
    • Recognize the toxicities and quality of life implications of radiation therapy for bladder cancer

Michael S. Lee, MD

Assistant Professor of Medicine
Molecular Therapeutics
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Michael Lee from the UNC Lineberger Gastrointestinal Oncology group will describe relevant updates in systemic therapy for gastrointestinal cancers for health care providers throughout the state of North Carolina.

Webinar Objectives

• • • Discuss optimal management for patients with advanced hepatocellular carcinoma with normal liver function
    • Discuss new targeted therapy options in subsets of patients with metastatic colorectal cancer
    • Discuss optimal duration and course of adjuvant therapy for stage III colon cancer

Siddharth Sheth, DO, MPH

Assistant Professor
Assistant Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Siddharth Sheth from the UNC Lineberger Head and Neck Oncology group will describe relevant updates in systemic therapy for head and neck cancers for health care providers throughout the state of North Carolina. Additional topical management considerations or recommendations for this patient population may also be presented.

Webinar Objectives

• • • Describe key risk factors and critical anatomy associated with head and neck cancers
    • Differentiate between HPV associated head and neck cancer and non-HPV associated head and neck cancer in relation to biology, prognosis, and treatment
    • Explain findings from seminal head and neck cancer clinical trials since 2018

Frances Collichio, MD

Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Frances Collichio from the UNC Lineberger Melanoma group will describe relevant updates in understanding and managing toxicities of immunotherapies for health care providers throughout the state of North Carolina.

Webinar Objectives

• • • Identify and grade common immune related adverse events
    • Identify rare but serious immune related adverse events
    • Recognize when combinations, sequences or comorbidities can increase the risk and severity of immune related adverse events

Joshua Zeidner, MD

Assistant Professor
Clinical Research
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Joshua Zeidner will discuss updates in the diagnostic testing and prognostic subclassifications of AML which drive therapeutic decisions. This presentation will highlight perceived paradigm shifts for AML and older adults.

Webinar Objectives

• • • Discuss pathogenesis/etiology of AML
    • Explain diagnostic testing in AML
    • Describe management of AML in older patient populations in the context of recent drug approvals

Young Whang, MD, PhD

Associate Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Young Whang, MD, from the UNC Lineberger Genitourinary Oncology group will describe relevant updates in systemic therapy for prostate cancers for health care providers throughout the state of North Carolina. Additional topical management considerations or recommendations for this patient population may also be presented.

Webinar Objectives

• • • Describe the recent advances in the available options in treatment of metastatic hormone sensitive prostate cancer
    • Describe the recent advances in understanding the genetics of prostate cancer and implications for treatment of metastatic prostate cancer
    • Describe the recent advances in optimizing the sequencing of treatment of metastatic castration resistant prostate cancer

Andrew Wang, MD

Associate Professor
Department of Radiation Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Radiotherapy plays an important part in many cancer treatment plans; however, recent studies suggest that we can make better use of radiotherapy in some instances. Dr. Andrew Wang, of Wang Laboratory at UNC Lineberger Comprehensive Cancer Center, will help us navigate this changing landscape.

Webinar Objectives

• • • Identify patients that are appropriate for radiotherapy
    • Understand different types of radiotherapy
    • Recognize new indications for radiotherapy in prostate cancer patients and oligometastsis

Paola A. Gehrig, MD

Professor and Director, UNC Gynecologic Oncology
Department of Obstetrics and Gynecology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Paola A. Gehrig, MD, will discuss the management of cervical cancer and cervical dysplasia in pregnancy and the impact of each condition on the other. She will also discuss the management of pelvic masses and ovarian cancer in pregnancy and the impact of each condition on the other.

Webinar Objectives

• • • Discuss the general diagnostic and therapeutic principles including systemic for gynecologic malignancies in pregnancy.
    • Discuss the management of cervical dysplasia and pelvic masses in pregnancy.
    • Discuss the impact of a cancer diagnosis on the pregnancy and vice versa.

Bhisham Chera, MD

Associate Professor
Associate Chair, Clinical Operations and Improvement
Director, Patient Safety and Quality
Department of Radiation Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

The Head and Neck Oncology program is actively pursuing a number of clinical trials at UNC. Dr. Bhisham S. Chera will provide an update on some of these trials.

Webinar Objectives

• • • Discuss de-intensified treatment for patients with HPV-Associated Oropharynx Cancer
    • Define the utility of circulating HPV DNA
    • Describe newer de-intensification treatment strategies

Brian Colwell Jensen, MD

Associate Professor of Medicine
Division of Cardiology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

When there is damage to the heart muscle, we call this cardiotoxicity. Brian Jensen, MD, will talk about underlying mechanisms for the cardiotoxicity of kinase inhibitors used to treat cancer.

Webinar Objectives

• • • Recognize that kinase inhibitors used in cancer treatment can have adverse cardiovascular effects
    • Recall potential mechanisms for kinase inhibitor-induced cardiotoxicity
    • Describe current options for treatment of metastatic hormone sensitive prostate cancer.
    • Identify potential treatments for kinase inhibitor cardiovascular toxicity

Jared Weiss, MD

Associate Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Tracy Rose, MD, MPH

Assistant Professor
Division of Hematology/Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

The American Society of Clinical Oncology (ASCO) hosts an annual conference that features some of the latest oncology research. Join us as our speaker highlights some of the top presentations from this year’s ASCO conference. This Webinar focuses on the top research for Lung and Genitourinary Cancers at the 2019 ASCO conference.

Webinar Objectives

• • • Discuss advances in TKIs in NSCLC.
    • Review advances in immunotherapy in NSCLC.
    • Describe current options for treatment of metastatic hormone sensitive prostate cancer.
    • Identify new combination treatments for metastatic clear cell renal cell carcinoma and sarcomatoid RCC.

Autumn McRee, MD

Associate Professor, Division of Hematology/Oncology
Director, Clinical Trials for GI Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Emily Ray, MD, MPH

Nominated Clinical Assistant Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

The American Society of Clinical Oncology (ASCO) hosts an annual conference that features some of the latest oncology research. Join us as our speaker highlights some of the top presentations from this year’s ASCO conference. This Webinar focuses on the top research for Gastrointestinal and Breast Cancers at the 2019 ASCO conference.

Webinar Objectives

• • • Explain the role of PARP inhibition in treating metastatic pancreatic cancer with germline BRCA mutations.
    • Discuss whether FOLFOXIRI should be considered 1st line standard of care in metastatic colorectal cancer.
    • Describe neoadjuvant and adjuvant therapy options for patients with HER2+ breast cancer.
    • Identify the principal findings of the MONALEESA-7 trial of endocrine therapy with or without ribociclib.

Lisa Carey, MD

Richardson and Marilyn Jacobs Preyer Distinguished Professorship for Breast Cancer Research</em
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Of women diagnosed with early-stage breast cancer, approximately 20% will develop metastatic disease. Metastatic disease is incurable, but increasingly controllable with modern therapies

Webinar Objectives

• • • Recognize the goals of management for metastatic breast cancer.
    • Describe the principles of treatment for hormone receptive-positive, HER2-positive, and triple negative breast cancer.
    • List the emerging research that may improve future treatment of patients with metastatic breast cancer.

Trevor Hackman, MD, FACS

Vice Chair, Department of Otolaryngology/Head and Neck Surgery
Assistant Professor, Department of Otolaryngology/Head and Neck Surgery
Director, Head and Neck Oncology Fellowship
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Trevor Hackman is the Director of the Head and Neck Oncology Fellowship and specializes in treatment of patients with diseases and disorders of the ear, nose, throat (ENT), with a focus in head and neck oncology. In this Webinar, he will talk about the Human Papillomavirus (HPV) in head and neck cancers in terms of epidemiology, vaccination, molecular/genomics, de-escalation, role of TORS, and immunotherapy.

Webinar Objectives

• • • Describe the epidemiology of Human Papilloma Virus (HPV) infection
    • Identify the epidemiology of HPV-related head and neck cancer
    • Discuss the impacts of HPV on treatment and prognosis
    • Differentiate treatment options, areas of exploration & prevention

Raj S. Pruthi, MD

Chair, Department of Urology
Professor, Urologic Oncology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

The Webinar will evaluate the recent improvements in patients undergoing radical cystectomy for bladder cancer (including peri-operative chemotherapy and robotic surgery) and will describe some of the obstacles to providing optimal care that still exist.

Webinar Objectives

• • • Recognize the advances in surgical treatment of invasive bladder
    • Understand obstacles to optimal outcomes in bladder cancer patients
    • Identify the advances in the peri-operative management of cystectomy patients

Yuliya Pylayeva-Gupta, PhD

Assistant Professor
Department of Genetics
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

This Webinar will review the current understanding of the role of immune system in pancreatic cancer and provide insight into development of the latest immune-based therapies aimed at treating patients with pancreatic cancer.

Webinar Objectives

• • • Describe the etiology and current treatment of pancreatic ductal adenocarcinoma.
    • Discuss the challenges imposed by tumor microenvironment in treating pancreatic cancer.
    • Discuss novel approaches to immunotherapy in pancreatic cancer.

Stephan Moll, MD

Professor of Medicine
Hemophilia and Thrombosis Center
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Anne W. Beaven, MD

Associate Professor of Medicine
Director, Lymphoma Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Each year, the American Society of Hematology (ASH) hosts a conference highlighting some of the latest hematologic oncology research. Join us as our speakers highlight some of the top presentations on Non-Malignant Hematology and Lymphoma from this year’s ASH conference.
Dr. Beaven will present a concise review of the most relevant and practice changing lymphoma abstracts that were presented at the American Society of Hematology Annual Meeting in 2018.

Webinar Objectives

• • • Discuss the risk/benefit of prophylactic dose apixaban or rivaroxaban in ambulatory cancer patients starting chemotherapy, who have never had a DVT or PE.
    • Decide which anticoagulant is best to use in the severely obese patient and the patient who has had bariatric surgery who has an indication for full dose anticoagulation.
    • Describe the use of brentuximab vedotin as front line treatment of patients with CD30+ Peripheral T Cell Lymphoma.
    • Recognize that a short course of RCHOP chemotherapy alone may be effective in treatment of young patients with low risk DLBCL.

Brandi Reeves, MD

Professor of Medicine
Malignant Hematology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Matthew Foster, MD

Associate Professor, Clinical Research
Leukemia, Lymphoma, and Myeloma Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Each year, the American Society of Hematology (ASH) hosts a conference highlighting some of the latest hematologic oncology research. Join us as our speakers discuss some of the top presentations on Myeloma and Leukemia/MDS from this year’s ASH conference.

Webinar Objectives

• • • Compare the outcomes of previously untreated patients with chronic lymphocytic leukemia (CLL) who are treated with ibrutinib versus those treated with chemo-therapy.
    • Describe which patients with myelodysplastic syndromes may benefit from treatment with luspatercept.
    • Identify appropriate patients with myelodysplastic syndromes for iron chelation with defarasirox and list adverse outcomes that may be prevented by using this agent.

Natalie Grover, MD

Assistant Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

This Webinar will give an overview of CAR-T cells, discuss recent clinical trial results and FDA approvals as well as current clinical applications. This Webinar will also cover the management of the unique toxicities of CAR-T therapy. Finally, this Webinar will discuss some of the ongoing trial of CAR-T therapy as well as future directions of the field.

Webinar Objectives

• • • Discuss the current approved indications for CAR-T cells.
    • Describe presentation and management of unique toxicities associated with CAR-T therapy.
    • Describe challenges of developing CAR-T cells for solid tumors.

Eliza Park, MD

Assistant Professor, Department of Psychiatry
Clinical Assistant Professor, Clinical Research
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Depression and anxiety disorders commonly occur among patients with cancer and their family caregivers. This Webinar focuses on the common symptoms and management strategies for depression and anxiety disorders in patients with cancer and their family members.

Webinar Objectives

• • • Describe the epidemiology of depression and anxiety disorders in patients with cancer and their family caregivers.
    • Recognize the initial pharmacologic and non-pharmacologic treatment strategies for anxiety and depression in cancer.
    • Identify the major risk factors for suicide among patients with cancer.

Claudio L. Battaglini, PhD, FACSM

Professor, Cancer Prevention and Control
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Bill Wood, MD

Associate Professor, Clinical Research
Leukemia, Lymphoma, and Myeloma Program
Bone Marrow and Stem Cell Transplantation Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

In this presentation, Dr. Wood and Dr. Battaglini will review the importance of physical function (also referred to as physical performance) in patients receiving treatment for cancer, followed by a review of the mechanisms and evidence base supporting the role of exercise in improving cancer outcomes. Examples of aerobic and resistance exercise interventions will be discussed.

Webinar Objectives

• • • Discuss the relevance of physical performance in predicting outcomes and the patient experience in individuals who have received treatment for cancer.
    • Differentiate methods for measuring and modeling physical performance in cancer.
    • Describe the benefits that aerobic, resistance, and combined exercise interventions have upon physical performance and outcomes in cancer.

Simon Khagi, MD

Assistant Professor, Medicine and Neurosurgery
Director, UNC Brain Tumor Program
Department of Neurosurgery
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Glioblastoma is a devastating disease with a survival that is measured in months. The recent FDA approval of the Optune device for the treatment of newly-diagnosed glioblastoma was a paradigm shift in the field of neuro-oncology. We will focus our discussion on the biological underpinnings of this device and clinical data supporting its use.

Webinar Objectives

• • • Discuss the outcomes and treatment of glioblastoma before the introduction of Optune
    • Explain the mechanism of actions and early research that led to the approval of Optune by the FDA
    • Describe the evolving role of Optune in the management of glioblastoma

Temitope O. Keku, MSPH, PhD

Associate Professor, Cancer Epidemiology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

The gut microbiome is responsible for regulation of many functions in humans including metabolism, immune responses and inflammation. This Webinar will focus on the gut microbiome and their interactions with the host to influence cancer treatment outcomes.

Webinar Objectives

• • • Describe the gut microbiome and how changes in composition influence health and disease
    • Understand how the gut microbiome interacts with the immune system to affect response to cancer therapy, especially immunotherapy
    • Future directions and strategies to manipulate the gut microbiome to improve clinical outcomes in cancer patients

Michael Lee, MD

Assistant Professor, Molecular Therapeutics
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Treatment of metastatic colorectal cancer has continued to evolve over the last several years, with emerging identification of biomarkers that underlie heterogeneity of responses to new and existing therapy. Ongoing clinical research seeks to identify new therapeutic options in molecularly-defined subgroups of patients. We will review the most exciting and clinically impactful research findings in this presentation.

Webinar Objectives

• • • Discuss important clinicopathologic features underlying the biology of colorectal cancer
    • Describe varying sequences of therapies in management of metastatic colorectal cancer
    • Describe biomarkers that guide selection and personalization of therapies for patients with advanced colorectal cancer

Lisa Carey, MD

Richardson and Marilyn Jacobs Preyer Distinguished Professorship for Breast Cancer Research
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Dr. Carey will discuss the anatomic and genomic variables that impact on (neo)adjuvant decision-making in breast cancer and the current treatment algorithms that allow rational escalation and de-escalation of systemic therapy.

Webinar Objectives

• • • Understand the roles of stage, hormone receptors, and biologic assays in determining systemic treatment and outcome.
    • Recognize the features that make a tumor more appropriate for neoadjuvant systemic therapy and the implications of this approach to therapy.
    • Determine the optimal regimens for triple negative, hormone receptor-positive, and HER2-positive breast cancer.

Joshua Zeidner, MD

Assistant Professor
Clinical Research
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Acute Myeloid Leukemia (AML) is an aggressive hematologic malignancy that affects approximately 20,000 patients each year in the United States. Management of AML has changed little over the last several decades and outcomes remain unsatisfactory. However, recent drug discoveries and approvals show tremendous promise. This presentation will review the current treatment armamentarium of AML highlighting novel concepts and investigational agents in development.

Webinar Objectives

• • • Discuss pathogenesis/etiology of AML
    • Identify diagnostic testing in AML
    • Discuss management of AML in younger and older patient populations in the context of recent drug approvals, highlighting some investigational agents in development

Matthew I. Milowsky, MD

Professor of Medicine
Clinical Professor, Urology
Section Chief, Genitourinary Oncology Service
Co-Director, Urologic Oncology Program
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

The Genitourinary Cancers Symposium co-sponsored by the American Society of Clinical Oncology (ASCO), American Society for Radiation Oncology (ASTRO), and Society of Urologic Oncology (SUO) provides some of the latest findings in genitourinary cancers (including prostate, bladder, kidney and testicular cancers). This Webinar will highlight some of the cutting-edge research findings presented at the 2018 meeting.

Webinar Objectives

• • • Describe recent advances using antiandrogen therapy in patients with nonmetastatic castration-resistant prostate cancer.
    • Discuss the use of novel combination therapy approaches with immune checkpoint inhibitors in metastatic renal cell cancer.
    • Review the evolving landscape for immunotherapy in patients with advanced bladder cancer.

Thomas Alexander, MD, MPH

Assistant Professor, Department of Pediatrics
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

Children with cancer, and their clinicians, face a unique spectrum of challenges. Differences in diagnosis, biology, treatment toxicity, and impact on social development require focused teams of researchers, healthcare providers, psychologist, and social workers. Novel diagnostic and treatment paradigms require intricate systems for data interpretation and therapy delivery, but come with a hope of improved survival and quality of life.

Webinar Objectives

• • • Describe the epidemiology of childhood cancer and the growing number of survivors
    • List the challenges and opportunities facing clinicians (and children and families) during intensive multi-modal therapy
    • Discuss novel frontiers of precision medicine and immunotherapy in pediatric oncology

Chad Pecot, MD

Assistant Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

This Webinar will describe the rationale behind using immunotherapy in lung cancer, the current standard of care use of immunotherapy, and future directions.

Webinar Objectives

• • • Describe basic tumor immunology and concepts regarding use of the immune system to combat cancer.
    • Identify current FDA approved immunotherapies in lung cancer.
    • Recognize promising future directions in immunotherapy.

Jason Akulian, MD, MPH

Assistant Professor of Medicine
Director, Interventional Pulmonology
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Webinar Description

The most common lung cancers are known to have diverse pathological features and recent research has further identified distinct diseases with genetic and cellular heterogeneity. This Webinar will provide strategies for managing this heterogeneity during clinical evaluation and treatment of patients.

Webinar Objectives

• • • Define lung cancer heterogeneity.
    • Discuss lung cancer heterogeneity.
    • Identify treatment decisions based on a patient’s lung cancer heterogeneity.