Chapel Hill - A family of proteins is yielding new information about how it contributes to the development of gastrointestinal disease and cancer. A team of UNC scientists reports that in pre-clinical models, the absence of a protein called NLRP12 significantly increases susceptibility to colitis-associated colon cancer.
UNC Health Care will offer free screenings during Oral, Head and Neck Cancer Awareness Week, on Wednesday, April 25, from 1 - 4 p.m. in the Ear, Nose, & Throat Clinic on the ground floor of the N.C. Neurosciences Hospital.
Chapel Hill, NC – In a paper published today in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases “en masse”, enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies.
Chapel Hill - Anyone who’s tried a weekend home improvement project knows that to do a job right, you’ve got to have the right tools. For cells, these “tools” are proteins encoded by genes.
Dr. Nancy DeMore and UNC colleagues present triple-negative breast cancer finding at national meeting
Nancy DeMore, MD, and colleagues presented an abstract at the recent Society of Surgical Oncology 65th annual cancer symposium held in Orlando, Florida in March. Dr. DeMore is an associate professor of surgery and a member of UNC Lineberger.
UNC Cancer Care’s neuro-oncology program will recognize Ependymoma Awareness Day on April 19th, as part of the program’s overall efforts to increase public awareness of this rare tumor and the need for clinical studies to improve early diagnosis, standardize treatment and improve the health status of those living with this disease.
UNC-led team offers clinical, research agenda
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in recent articles in The News & Observer and the Scientific American blog.
Chapel Hill - In a clinical trial of an experimental drug to treat thyroid cancer, UNC and six other institutions report the first evidence in this tumor that targeting therapy to an oncogene documented to be present in the patient receiving therapy may be associated with clinical benefit.
UNC Lineberger faculty members Ned Sharpless, MD, and Adam Zanation, MD, were honored for their achievements by Triangle Business Journal as 2012 Health Care Heroes.
David Ollila, MD, and Craig Burkhart, MD, spoke about teenage tanning bed use at a Child Fatality Task Force committee meeting on March 26, 2012. They discussed the option of banning teenagers below the age of 18 from tanning bed use.
The Lustgarten Foundation, the nation’s largest foundation dedicated solely to funding pancreatic cancer research, has awarded Channing Der, PhD, a $1.165 million grant to identify promising drug combinations for potential future use in clinical trials.
John Baron, MD, was interviewed by Charles Bankhead of MedPage Today on March 21, 2012 to give his perspective on three recently published reviews in "The Lancet" and "The Lancet Oncology." The reviews suggest that "regular aspirin use leads to significant reductions in the risk of cancer, metastasis, and cancer mortality."
A team of scientists, including several from UNC Lineberger, has identified predictive genetic biomarkers in pre-clinical models that affect response to therapy for non-small cell lung cancer (NSCLC). The study was done in parallel to an ongoing clinical trial among lung cancer patients at multiple institutions.
Jared Weiss, MD, gave a podcast titled "2011 Highlights in Lung Cancer" that was posted on cancergrace.org on March 15, 2012. In the podcast, Dr. Weiss talks about highlights in lung cancer from 2011 and also answers questions.
Internationally renowned virologist; past president of national cancer and international virology associations; National Academy of Science Institute of Medicine member; North Carolina Award for Science winner; revered mentor to faculty, fellows, medical and graduate students; Berryhill Lecturer; proud grandfather; dedicated squash and tennis player; and recent honoree at his eightieth birthday.
N.E.D. is a rock band. The members of the band are gynecologic cancer surgeons from all over the country and two of them, Dr. John Boggess and Dr. John Soper, work here at UNC Health Care.
Drs. Christine E. Kistler and Adam Goldstein discuss how clinicians can better have conversations about the balance between short-term risk of adverse cardiovascular events associated with taking Chantix compared to the long-term reduction in the risk of death that results from smoking cessation.
Enduring subtle, insidious acts of racial discrimination is enough to depress anyone, but African-American men who believe that they should respond to stress with stoicism and emotional control experience more depression symptoms, according to new findings from the University of North Carolina at Chapel Hill.
A study of cervical cancer incidence and mortality in North Carolina has revealed areas where rates are unusually high.
The Center for Integrative Chemical Biology and Drug Discovery at the University of North Carolina at Chapel Hill has received a contract from SAIC-Frederick, Inc. to develop potential drug leads for treating renal cell carcinoma, the most common type of kidney cancer in adults.
Small DNA circles found outside the chromosomes in mammalian cells and tissues, including human cells
CHAPEL HILL, N.C. – Researchers from the University of North Carolina at Chapel Hill have helped identify a new DNA entity in mammalian cells and provided evidence that their generation leaves behind deletions in different locations of the cells’ genetic program, or genome.
Tobacco companies have enlisted convenience stores as their most important partners in marketing tobacco products and fighting policies that reduce tobacco use, according to a report released today by leading public health organizations, including The University of North Carolina Gillings School of Global Public Health.
Timothy Gershon, MD, PhD, assistant professor of neurology, has received a four-year National Institutes of Health Mentored Clinical Scientist Research Career Development Award grant from the National Institute of Neurologic Disease and Stroke.