UNC Lineberger News

UNC Bone Marrow and Stem Cell Transplantation Program achieves outstanding outcomes

Chapel Hill, NC –A medical procedure called allogeneic hematopoietic cell transplantation, commonly known as a bone marrow or stem cell transplant, is the only known curative option for many patients with life-threatening blood-borne cancers such as leukemia and lymphoma.

UNC Bone Marrow and Stem Cell Transplantation Program achieves outstanding outcomes - Read More…

Thriving on science: in depth with Jason Lieb

Thriving on science: in depth with Jason Lieb

Jason Lieb likes to mix it up. A triathlete, he enjoys running, swimming and cycling. In his lab, he works in several model systems: yeast, round worms (C. elegans), fruit flies (Drosophila melanogaster) and human cell lines.

Thriving on science: in depth with Jason Lieb - Read More…

Postdoctoral fellow receives DOD Visionary Fellowship Award

Postdoctoral fellow receives DOD Visionary Fellowship Award

Idoia Garcia, PhD, a postdoctoral fellow in the lab of Timothy Gershon, MD, PhD, has been awarded a Department of Defense Visionary Postdoctoral Fellowship Award. The peer-reviewed award is intended to support exceptionally talented recent medical or other doctoral graduates in their pursuit of cutting-edge, innovative, high-risk/high-impact cancer research during their postdoctoral fellowship.

Postdoctoral fellow receives DOD Visionary Fellowship Award - Read More…

Der receives grant funding for pancreatic cancer research

Der receives grant funding for pancreatic cancer research

Channing Der, PhD, Sarah Graham Kenan Professor of Pharmacology, received a two-year $200,000 American Association for Cancer Research Innovative grant from the Pancreatic Cancer Action Network. His grant will fund research on the mechanism of ERK inhibition resistance and ERK-dependent pancreatic cancer.

Der receives grant funding for pancreatic cancer research - Read More…

UNC scientist reports ways to improve breast cancer biomarker test

UNC scientist reports ways to improve breast cancer biomarker test

American and Spanish researchers report potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests.

UNC scientist reports ways to improve breast cancer biomarker test - Read More…

Review study makes recommendations to enhance Cancer Comparative Effectiveness Research

Which treatment for prostate cancer is most effective? Will a specific combination of cancer drugs increase patient survival for colon cancer? As the pace of scientific discovery continues to accelerate, patients and their providers face more choices and decisions about how to address their health care needs, and information that can help inform their decisions is often hard to find.

Review study makes recommendations to enhance Cancer Comparative Effectiveness Research - Read More…

Stem cells poised to self-destruct for the good of the embryo

Stem cells poised to self-destruct for the good of the embryo

Embryonic stem cells are primed to kill themselves if damage to their DNA makes them a threat to the developing embryo. UNC researchers reveal how they do it.

Stem cells poised to self-destruct for the good of the embryo - Read More…

DeSimone elected into National Academy of Sciences

DeSimone elected into National Academy of Sciences

Dr. Joseph DeSimone, PhD, Chancellor's Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill, has been elected into the National Academy of Sciences, one of the highest honors that a U.S. scientist or engineer can receive.

DeSimone elected into National Academy of Sciences - Read More…

Milowsky comments on new therapies for bladder cancer

Milowsky comments on new therapies for bladder cancer

Matthew Milowsky, MD, was recently quoted in the online journal Health News Digest on new therapies for bladder cancer.

Milowsky comments on new therapies for bladder cancer - Read More…

Joseph S. Pagano receives 2012 Battle Distinguished Cancer Research Award

Joseph S. Pagano receives 2012 Battle Distinguished Cancer Research Award

Joseph S. Pagano, MD, has been awarded the fifth annual Hyman L. Battle Distinguished Cancer Research Award in recognition of his accomplishments in cancer research. Dr. Pagano is the director emeritus of UNC Lineberger Comprehensive Cancer Center.

Joseph S. Pagano receives 2012 Battle Distinguished Cancer Research Award - Read More…

UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery

UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery

Current nanomedicine research has focused on the delivery of established and novel therapeutics. But a UNC team is taking a different approach.

UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery - Read More…

36th Annual UNC Lineberger Scientific Symposium

UNC Lineberger’s 36th annual scientific symposium drew large crowds, with over 450 participants.

36th Annual UNC Lineberger Scientific Symposium - Read More…

Armistead receives Mentored Clinical Scientist Development Award

Armistead receives Mentored Clinical Scientist Development Award

Paul Armistead, MD, PhD, has received a grant of more than $396,000 from the National Heart, Lung and Blood Institute (part of the National Institutes of Health) to study leukemia stem cell-associated minor histocompatibility antigens.

Armistead receives Mentored Clinical Scientist Development Award - Read More…

UNC junior’s research honored at American Association for Cancer Research meeting

UNC junior’s research honored at American Association for Cancer Research meeting

UNC junior Molly DeCristo attended her first international scientific meeting, but not just as a participant. The American Association for Cancer Research (AACR) honored her poster with a rosette, judging it as “highly rated,” among the top 2.5 percent of those submitted.

UNC junior’s research honored at American Association for Cancer Research meeting - Read More…

Joyce Wilson: On Trips of a Lifetime, Planned and Unplanned

A Wayne County woman doesn’t let cancer, its treatment or its recurrence get in the way of her plans to attend her oldest granddaughter’s high school graduation or her own 45th high school reunion.

Joyce Wilson: On Trips of a Lifetime, Planned and Unplanned - Read More…

Intensity Modulated Radiation Therapy optimal for localized prostate cancer

Chapel Hill - A treatment for localized prostate cancer known as Intensity Modulated Radiation Therapy (IMRT) is better than conventional conformal radiation therapy (CRT) for reducing certain side effects and preventing cancer recurrence, according to a study published in the April 18, 2012 issue of the Journal of the American Medical Association. In 2012, approximately 241,740 American men will be diagnosed with prostate cancer.

Intensity Modulated Radiation Therapy optimal for localized prostate cancer - Read More…

International panel recommends new model for breast cancer care

CHAPEL HILL, N.C. - As the number of breast cancer survivors increases, now estimated at 2.8 million, more will be living with the chronic effects of cancer treatments or with advanced disease.

International panel recommends new model for breast cancer care - Read More…

Coghill receives grant to study graft versus host disease

Coghill receives grant to study graft versus host disease

James Coghill, MD, has received a grant of more than $529,000 from the National Heart, Lung and Blood Institute (part of the National Institutes of Health) to study a promising target for new therapies to combat graft versus host disease, a serious complication of treatment for many blood cancers.

Coghill receives grant to study graft versus host disease - Read More…

UNC scientists describe protein that protects against colon cancer

Chapel Hill - A family of proteins is yielding new information about how it contributes to the development of gastrointestinal disease and cancer. A team of UNC scientists reports that in pre-clinical models, the absence of a protein called NLRP12 significantly increases susceptibility to colitis-associated colon cancer.

UNC scientists describe protein that protects against colon cancer - Read More…

Three-dimensional RNA modeling opens scientific doors

Chapel Hill, NC – In a paper published today in the journal Nature Methods, a team from the University of North Carolina at Chapel Hill demonstrates a simple, cost-effective technique for three-dimensional RNA structure prediction that will help scientists understand the structures, and ultimately the functions, of the RNA molecules that dictate almost every aspect of human cell behavior. When cell behavior goes wrong, diseases – including cancer and metabolic disorders – can be the result.

Three-dimensional RNA modeling opens scientific doors - Read More…

UNC scientists describe protein that protects against colon cancer

Chapel Hill - A family of proteins is yielding new information about how it contributes to the development of gastrointestinal disease and cancer. A team of UNC scientists reports that in pre-clinical models, the absence of a protein called NLRP12 significantly increases susceptibility to colitis-associated colon cancer.

UNC scientists describe protein that protects against colon cancer - Read More…

Ten minutes could save your life: FREE Head & Neck Cancer Screenings

UNC Health Care will offer free screenings during Oral, Head and Neck Cancer Awareness Week, on Wednesday, April 25, from 1 - 4 p.m. in the Ear, Nose, & Throat Clinic on the ground floor of the N.C. Neurosciences Hospital.

Ten minutes could save your life: FREE Head & Neck Cancer Screenings - Read More…

Kinase test may yield big gains for drug-resistant cancers

Chapel Hill, NC – In a paper published today in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases “en masse”, enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies.

Kinase test may yield big gains for drug-resistant cancers - Read More…