News

Disrupting palladin in CAFs

Disrupting palladin in CAFs

Using pharmacological inhibitors and gene-silencing approaches, Otey and the research team discovered that disrupting palladin in CAFs reduced the ability of the cells to form invadopodia.

Disrupting palladin in CAFs - Read More…

Storming the gates – UNC research probes how pancreatic cancers metastasize

Storming the gates – UNC research probes how pancreatic cancers metastasize

Researchers at the University of North Carolina at Chapel Hill have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts of the body.

Storming the gates – UNC research probes how pancreatic cancers metastasize - Read More…

Lymphedema therapy provides relief for cancer patients

“It’s a lifesaver.” That’s how Frances Patterson, a breast cancer patient, describes the therapy she receives for lymphedema through the UNC Comprehensive Cancer Support Program.

Lymphedema therapy provides relief for cancer patients - Read More…

Smithies named to first class of the Fellows of the AACR Academy

Smithies named to first class of the Fellows of the AACR Academy

Oliver Smithies did not set out to become one of the world’s foremost pioneers in cancer research. He merely had a question that needed answering.

Smithies named to first class of the Fellows of the AACR Academy - Read More…

'Your Phone Versus Your Heart' - Fredrickson in the New York Times

Barbara Fredrickson, professor of psychology and UNC Lineberger member, writes in an editorial in the New York Times that the physical and psychological tools that allow us to relate to others can diminish with lack of use.

'Your Phone Versus Your Heart' - Fredrickson in the New York Times - Read More…

Evans on WRAL - Researchers push for new healthcare screening strategy

James Evans, director of UNC's Clinical Cancer Genetics program and UNC Lineberger member, says it is time for a public health strategy that focuses on genetic testing of healthy adults.

Evans on WRAL - Researchers push for new healthcare screening strategy - Read More…

Sills raises awareness about her rare cancer

Craven County resident, Cindy Sills, has alveolar rhabdomyosarcoma, a cancerous tumor of the muscles that are attached to bones. She and her husband work to raise awareness of rare rare soft-tissue cancer.

Sills raises awareness about her rare cancer - Read More…

Researchers identify genetic sequence that helps to coordinate synthesis of DNA-packaging proteins

Researchers identify genetic sequence that helps to coordinate synthesis of DNA-packaging proteins

Research conducted in fruit flies at the University of North Carolina School of Medicine has pinpointed a specific DNA sequence that both triggers the formation of the “histone locus body” and turns on all the histone genes in the entire block.

Researchers identify genetic sequence that helps to coordinate synthesis of DNA-packaging proteins - Read More…

Today Show features Single Fathers Due to Cancer

NBC's Today Show spotlighted the first-of-its-kind program designed to help single dad's who have lost a spouse to cancer. NBC’s Dr. Nancy Snyderman reports on the group's efforts.

Today Show features Single Fathers Due to Cancer - Read More…

Single Fathers Due to Cancer featured in Clinical Journal of Oncology Nursing

Men who have dependent children and whose spouses or partners died from cancer are an overlooked population. These fathers face unique challenges not addressed by traditional grief support groups that often attract an older, female population.

Single Fathers Due to Cancer featured in Clinical Journal of Oncology Nursing - Read More…

UNC-Duke Pro Bono Project Offers Free Legal Services to Cancer Patients

UNC-Duke Pro Bono Project Offers Free Legal Services to Cancer Patients

Cancer patients at UNC and Duke have one less thing to worry about, thanks to the recently launched Cancer Pro Bono Legal Project. This cutting-edge collaboration among the law schools and cancer centers at the two universities and the North Carolina Bar Association offers free legal services to local cancer patients. The project has won funding from the Kenan Biddle Foundation as well as the North Carolina Bar Foundation.

UNC-Duke Pro Bono Project Offers Free Legal Services to Cancer Patients - Read More…

African Americans experience longer delay between prostate cancer diagnosis and treatment

African Americans experience longer delay between prostate cancer diagnosis and treatment

African American men on average wait a week longer than their Caucasian counterparts between the initial diagnosis of prostate cancer and treatment, according to University of North Carolina researchers.

African Americans experience longer delay between prostate cancer diagnosis and treatment - Read More…

Muss discusses treating older cancer patients at OncLive

Hyman B. Muss, MD, Professor of Medicine, Director of Geriatric Oncology, Division of Hematology and Oncology, Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill School of Medicine, discusses the need for a team environment when treating an older patient at OncLive.

Muss discusses treating older cancer patients at OncLive - Read More…

Vera Montague

Vera Montague

It’s given my daughter power of attorney over me. It’s convenient for me to get it done when I’m coming to clinic. It gives my daughter the authority so I don’t have to worry about it if something happens to me.

Vera Montague - Read More…

Dat Nguyen

Dat Nguyen

Law student Jason Jones works with Dat Nguyen of Chapel Hill.

Dat Nguyen - Read More…

For the first time, researchers isolate adult stem cells from human intestinal tissue

The accomplishment provides a much-needed resource for scientists eager to uncover the true mechanisms of human stem cell biology. It also enables them to explore new tactics to treat inflammatory bowel disease or to ameliorate the side effects of chemotherapy and radiation, which often damage the gut.

For the first time, researchers isolate adult stem cells from human intestinal tissue - Read More…

Lancet Oncology - Building a Pathology Laboratory in Malawi

Lancet Oncology - Building a Pathology Laboratory in Malawi

Satish Gopal, MD, MPH, assistant professor in the divisions of hematology/oncology and infectious diseases at the UNC School of Medicine, describes his experiences in assisting Kamuzu Central Hospital in the creation of a lab to diagnose and research cancer in Malawi.

Lancet Oncology - Building a Pathology Laboratory in Malawi - Read More…

Hayes - Genomic alterations in head and neck cancers are possible therapy targets

Hayes - Genomic alterations in head and neck cancers are possible therapy targets

Neil Hayes, MD, MPH, associate professor in UNC's Division of Hematology and Oncology, presented on the patterns of genomic alterations in head and neck squamous cell carcinomas (HNSCC) at the AACR's 2013 Annual Meeting in Washington, D.C.

Hayes - Genomic alterations in head and neck cancers are possible therapy targets - Read More…

Carey discusses metastatic breast cancer at OncLive

Lisa A. Carey, MD, Medical Director of the UNC Breast Center, the Chief of Hematology/Oncology, the Physician-in-Chief of the N.C. Cancer Hospital, and UNC Lineberger member, discusses the use of everolimus in the metastatic and adjuvant settings of breast cancer.

Carey discusses metastatic breast cancer at OncLive - Read More…

Hepatitis A virus discovered to cloak itself in membranes hijacked from infected cells

A team led by Dr. Stanley Lemon discovered that hepatitis A virus does not have an envelope when found in the environment, but acquires one from the cells that it grows in within the liver. It circulates in the blood completely cloaked in these membranes.

Hepatitis A virus discovered to cloak itself in membranes hijacked from infected cells - Read More…

Dokholyan lab engineers 'protein switch' to dissect role of cancer's key players

Researchers at the University of North Carolina at Chapel Hill School of Medicine have "rationally rewired" some of the cell's smallest components to create proteins that can be switched on or off by command. These "protein switches" can be used to interrogate the inner workings of each cell, helping scientists uncover the molecular mechanisms of human health and disease.

Dokholyan lab engineers 'protein switch' to dissect role of cancer's key players - Read More…

Evans quoted in New York Times on Supreme Court  gene patent case

Evans quoted in New York Times on Supreme Court gene patent case

James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted about a case before the U.S. Supreme Court involving Myriad Genetics attempts to patent two human genes related to breast and ovarian cancer.

Evans quoted in New York Times on Supreme Court gene patent case - Read More…

Family House Diaries: Claudia Laskow - A Sense of Humor Carries the Day

Family House Diaries: Claudia Laskow - A Sense of Humor Carries the Day

A Dare County real estate agent refuses to let a breast cancer diagnosis and its treatment detract from her trademark sense of humor and constant outreach to others.

Family House Diaries: Claudia Laskow - A Sense of Humor Carries the Day - Read More…

Bloom elected to American Academy of Arts and Sciences

Bloom elected to American Academy of Arts and Sciences

Kerry Steven Bloom, Thad L. Beyle Distinguished Professor of biology at the University of North Carolina at Chapel Hill, has been elected to the American Academy of Arts and Sciences, one of the nation’s oldest and most prestigious honorary societies and a leading center for independent policy research.

Bloom elected to American Academy of Arts and Sciences - Read More…

Bone Marrow and Stem Cell Transplant Program team participates in Spartan Race

A team from the UNC Bone Marrow and Stem Cell Transplant Program headed up by Tippu Khan, PharmD, BCOP and Nicole Frazier, RN, BSN participated in an epic journey which included leaping over fire, trekking through waste-high mud, tossing spears, dodging attacks and most of all braving near freezing temperatures in the driving rain. What is all this about? It's the Spartan Race, an event of pure primitive craziness that promises it's participants an experience they'll never forget.

Bone Marrow and Stem Cell Transplant Program team participates in Spartan Race - Read More…

 Varmus delivers third annual Oliver Smithies Nobel Symposium

Varmus delivers third annual Oliver Smithies Nobel Symposium

Dr. Harold E. Varmus, director of the National Cancer Institute at the National Institutes of Health and co-winner of the 1989 Nobel Prize in Physiology or Medicine for the discovery of the cellular origin of retroviral oncogenes, was invited to campus by UNC’s Nobel Laureate Dr. Oliver Smithies.

Varmus delivers third annual Oliver Smithies Nobel Symposium - Read More…

Sethi, MacNevin, Feng come out on top at 3rd Annual Oliver Smithies Nobel Symposium Postdoctoral Researcher Poster Forum

Sethi, MacNevin, Feng come out on top at 3rd Annual Oliver Smithies Nobel Symposium Postdoctoral Researcher Poster Forum

On Friday, April 19, from 2 p.m. to 4 p.m. in the MBRB at the School of Medicine, 44 university postdoctoral fellows gathered for a poster forum to present their research findings.

Sethi, MacNevin, Feng come out on top at 3rd Annual Oliver Smithies Nobel Symposium Postdoctoral Researcher Poster Forum - Read More…

Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma - Read More…

Ribisl quoted on NPR New York tobacco regulations

Ribisl quoted on NPR New York tobacco regulations

Kurt Ribisl, PhD, head of Cancer Prevention and Control Program at the UNC Lineberger Comprehensive Cancer Center, was interviewed by National Public Radio on New York City's proposal to raise the legal age to buy cigarettes to 21.

Ribisl quoted on NPR New York tobacco regulations - Read More…

Mayer named extraordinary nurse leader by Yale University

Mayer named extraordinary nurse leader by Yale University

Associate professor Deborah Mayer, PhD, RN, AOCN, FAAN and member of UNC Lineberger has been selected as an Extraordinary Nurse Leader by Yale University, the first independent university-based nursing school established in the United States. As part of its 90th anniversary celebration, Yale School of Nursing has selected 90 alumni who “embody the School’s mission of advancing better health care” to be honored at a ceremony in October 2013.

Mayer named extraordinary nurse leader by Yale University - Read More…

Anders lab shows advantage to nanotech delivery of therapy for breast cancer brain metastases

Anders lab shows advantage to nanotech delivery of therapy for breast cancer brain metastases

Breast cancer brain metastases present a challenge to clinicians because there are few systemic therapies capable of crossing the blood-brain barrier to control the disease. An international team, led by scientists at the University of North Carolina Lineberger Comprehensive Cancer Center, reports pre-clinical research showing improved efficacy of a PEGylated liposomal (encapsulated) anti-cancer agent compared with a non-liposomal formulation of the same drug in an intracranial model of breast cancer. Their results were published in the May 1, 2013 issue of PLOS ONE.

Anders lab shows advantage to nanotech delivery of therapy for breast cancer brain metastases - Read More…

UNC Lineberger 37th Annual Scientific Symposium

UNC Lineberger 37th Annual Scientific Symposium

Close to 450 people attended the 37th annual UNC Lineberger scientific symposium April 29 and 30, 2013. Symposium co-chairs were Jonathan Serody, MD, PhD, Elizabeth Thomas Chair of Medicine, and Jenny Ting, PhD, UNC Alumni Distinguished Professor of Microbiology and Immunology. Both spoke at the symposium.

UNC Lineberger 37th Annual Scientific Symposium - Read More…

Pruthi featured in OncLive on the dramatic shortage of urologists on the horizon

Raj Pruthi, MD, Chief of Urologic Surgery for the Urologic Oncology Program spoke at the annual meeting of the American Urological Association (AUA) in San Diego, California.

Pruthi featured in OncLive on the dramatic shortage of urologists on the horizon - Read More…

New York Times features Single Fathers Due to Cancer

Health reporter for the New York Times, Jane Brody, features the Single Fathers Due to Cancer program.

New York Times features Single Fathers Due to Cancer - Read More…

UNC Lineberger at the American Association for Cancer Research Annual Meeting

UNC Lineberger at the American Association for Cancer Research Annual Meeting

UNC Lineberger was well represented at the American Association for Cancer Research Annual Meeting held in Washington, DC.

UNC Lineberger at the American Association for Cancer Research Annual Meeting - Read More…

Self-collection of samples for HPV testing shows promise in detection of cervical cancer in Kenya

Self-collection of samples for HPV testing shows promise in detection of cervical cancer in Kenya

In Kenya, women face a cervical cancer mortality rate that is approximately 10 times as high as in the United States. A study by researchers at the University of North Carolina at Chapel Hill suggests that training women to self-collect genital samples to test for human papillomavirus (HPV), the causative agent of cervical cancer, can increase the coverage rates of cervical cancer screening. Higher screening coverage helps increase rates of detection of cervical lesions and ultimately treatment of the disease.

Self-collection of samples for HPV testing shows promise in detection of cervical cancer in Kenya - Read More…

Conlon lab uncovers molecular role of gene linked to blood vessel formation

University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.

Conlon lab uncovers molecular role of gene linked to blood vessel formation - Read More…

Muss on using tools to evaluate older patients

Hy Muss, MD, Director, Geriatric Oncology Program discusses evaluation tools for treating older patients on OncLive.

Muss on using tools to evaluate older patients - Read More…

Basch: Patient participation must play a larger role in research

Basch: Patient participation must play a larger role in research

Patients must take a larger role in participating in and assisting in determining priorities for medical research, according to an editorial published in an upcoming issue of the Journal of the American Medical Association.

Basch: Patient participation must play a larger role in research - Read More…

Smith interviewed by Agence France Presse on cervical cancer stigma in India

Smith interviewed by Agence France Presse on cervical cancer stigma in India

Jennifer Smith, PhD, MPH, research associate professor at the UNC Gillings School of Global Public Health and member of the UNC Lineberger Comprehensive Cancer Center, says that lack of awareness and stigma about the illness hinders prevention of the disease.

Smith interviewed by Agence France Presse on cervical cancer stigma in India - Read More…

Cancer genetics and BRCA 1 and BRCA 2 gene mutations

Q&A with UNC Lineberger members James P. Evans, MD, PhD; David Ollila, MD; Paola Gehrig, MD; and Keith D. Amos, MD, FACS.

Cancer genetics and BRCA 1 and BRCA 2 gene mutations - Read More…

Dees and Hayes named co-leaders of UNC Lineberger Clinical Research Program

Claire Dees, MD, and Neil Hayes, MD, MPH, have been appointed as co-leaders of the Clinical Research Program at UNC Lineberger Comprehensive Cancer Center. Dr. Dees and Hayes have extensive and complementary expertise in translational and clinical research. As co-leaders of the Clinical Research Program, they will help plan the efforts of UNC Lineberger’s physician researchers to move discoveries into innovative trials of new therapeutic approaches.

Dees and Hayes named co-leaders of UNC Lineberger Clinical Research Program - Read More…

Rimer awarded American Cancer Society Medal of Honor

Rimer awarded American Cancer Society Medal of Honor

Barbara K. Rimer, DrPH, Dean and Alumni Distinguished Professor of the University of North Carolina Gillings School of Global Public Health, has been awarded the American Cancer Society (ACS) Medal of Honor for her "seminal cancer research efforts."

Rimer awarded American Cancer Society Medal of Honor - Read More…

Endeavors - The Protein Sleuth

Endeavors profiles the work of Nancy Klauber-DeMore, MD, professor of surgery and a member of UNC Lineberger, in unraveling the mystery of whether the gene SFRP2 suppresses tumor growth.

Endeavors - The Protein Sleuth - Read More…

The secret lives (and deaths) of neurons

University of North Carolina School of Medicine researchers uncover surprising insights about how nerve cells rewire themselves, shedding light on a process linked with neurodegenerative diseases and neurodevelopmental disorders like schizophrenia and autism.

The secret lives (and deaths) of neurons - Read More…

chambers

chambers

Neurons can be cultured in one compartment of a microfluidic chamber (right side) and extend their axons through very small grooves into a separate compartment (left side).

chambers - Read More…

Charles Perou Receives 2013 Battle Cancer Research Award

Charles Perou Receives 2013 Battle Cancer Research Award

Charles Perou, PhD, the May Goldman Shaw Distinguished Professor of Molecular Oncology, has been honored with the 2013 Hyman L. Battle Distinguished Cancer Research Award in recognition of his accomplishments in cancer research. Dr. Perou is a member of UNC Lineberger Comprehensive Cancer Center.

Charles Perou Receives 2013 Battle Cancer Research Award - Read More…

IMRT may not be more effective than older radiation techniques after prostatectomy

Intensity-modulated radiation therapy has become the most commonly used type of radiation in prostate cancer, but research from the University of North Carolina suggests that the therapy may not be more effective than older, less expensive forms of radiation therapy in patients who have had a prostatectomy.

IMRT may not be more effective than older radiation techniques after prostatectomy - Read More…

Smith - Worldwide cervical cancer prevention initiative announced at Women Deliver Conference in Malaysia

Cervical cancer kills an estimated 275,000 women each year, and most of these deaths could be prevented with prophylactic HPV vaccination, routine cervical cancer screening and continuity to treatment. At the Women Deliver Conference in Kuala Lumpur, Malaysia, delegates and experts from around the world announced a global call to action to combat this preventable disease through collaboration with and information sharing by the world’s governments and health agencies on May 27, 2013.

Smith - Worldwide cervical cancer prevention initiative announced at Women Deliver Conference in Malaysia - Read More…

Wan - GATA-3 Is Important for the Regulation and Maintenance of the Immune System

The protein GATA-3 plays an important role in mammalian immune response, but its overall function in cell development and cancer formation is not well understood. In an effort to further define the importance of GATA-3, researchers at the University of North Carolina have traced how the protein performs important functions in CD8+T-cell type of the immune system.

Wan - GATA-3 Is Important for the Regulation and Maintenance of the Immune System - Read More…

The value of randomized clinical trials in radiation oncology clinical practice

The value of randomized clinical trials in radiation oncology clinical practice

Cancer patients, physicians and insurers want to be sure that whatever therapy is recommended and provided to patients is based on evidence, preferably results from randomized clinical trials. But are there enough clinical trials data to provide this level of confidence?

The value of randomized clinical trials in radiation oncology clinical practice - Read More…

Anders video interview on fertility preservation for female cancer patients

Dr. Carey Anders, MD, assistant professor of medicine, was interviewed in a new video on fertility preservation for female cancer patients produced by the American Society of Clinical Oncology. The video, titled “Discussing Fertility Preservation with Women,” was released in conjunction with ASCO updated guidelines and was shown at the 2013 ASCO annual meeting.

Anders video interview on fertility preservation for female cancer patients - Read More…

UNC to test interventions aimed at reducing colon cancer screening disparities

UNC to test interventions aimed at reducing colon cancer screening disparities

The study will focus on assessing the impact of a clinic-based intervention that includes having patients view a multimedia decision aid (in English or Spanish) before seeing their physician, as well as support from a bilingual patient “navigator” on completion of recommended colon cancer screening tests.

UNC to test interventions aimed at reducing colon cancer screening disparities - Read More…

UNC Lineberger's 2013 Scientific Retreat features "TED talks"

UNC Lineberger's 2013 Scientific Retreat features "TED talks"

More than 200 faculty, students and fellows gathered at the Carolina Club to hear ten-minute "TED talks" by 11 faculty recently recruited to UNC.

UNC Lineberger's 2013 Scientific Retreat features "TED talks" - Read More…

Pignone - Eligibility for aspirin for primary prevention in men increases when cancer mortality benefit added

Pignone - Eligibility for aspirin for primary prevention in men increases when cancer mortality benefit added

While aspirin has been shown to be effective in preventing heart attacks in men, it also increases the risk of gastrointestinal bleeding and possibly stroke, even at low doses. As such, national guidelines suggest that aspirin be used for prevention only in men at higher risk for cardiovascular events, so that the benefits of aspirin are greater than its adverse effects.

Pignone - Eligibility for aspirin for primary prevention in men increases when cancer mortality benefit added - Read More…

UNC Lineberger members present at 2013 ASCO Annual Meeting

UNC Lineberger members present at 2013 ASCO Annual Meeting

More than 15 members and associates of the UNC Lineberger Comprehensive Cancer Center presented their work to the attendees at the 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

UNC Lineberger members present at 2013 ASCO Annual Meeting - Read More…

Lucky 13 to bike across country to raise money for UNC Lineberger

Ten area teens will pedal with purpose this summer, riding some 3,700 miles over a 10-week period, from Maryland to Oregon. The group, dubbed “Lucky 13,” a play on the year “2013,” aims to raise $30,000 for UNC’s Lineberger Comprehensive Cancer Center, with a portion on the money going directly to serve pediatric cancer patients.

Lucky 13 to bike across country to raise money for UNC Lineberger - Read More…

Four UNC nursing graduate students awarded American Cancer Society scholarships

Four UNC nursing graduate students awarded American Cancer Society scholarships

Four UNC School of Nursing students have been awarded American Cancer Society Graduate Scholarships in Cancer Nursing Practice. The recipients are Sean Gallagher, RN; April Lenker, RN; Melissa Matson, RN; and Lori Walker, RN.

Four UNC nursing graduate students awarded American Cancer Society scholarships - Read More…

Millikan honored with posthumous Alumni Achievement Award from UC-Davis

Millikan honored with posthumous Alumni Achievement Award from UC-Davis

The late Robert Craft Millikan will be honored with a 2013 Alumni Achievement Award from the University of California at Davis School of Veterinary Medicine during the School's commencement ceremony on June 14.

Millikan honored with posthumous Alumni Achievement Award from UC-Davis - Read More…

Coach Hatchell’s blueberry patch supports UNC Lineberger

UNC women’s basketball Coach Sylvia Hatchell’s blueberry patch near Black Mountain, NC is almost ready for the summer picking season.

Coach Hatchell’s blueberry patch supports UNC Lineberger - Read More…

UNC researchers identify another piece of the “histone code” puzzle

UNC researchers identify another piece of the “histone code” puzzle

New research from the UNC School of Medicine has shown how a protein called UHRF1 “reads” the histone code in a specific way to perform an important cellular function.

UNC researchers identify another piece of the “histone code” puzzle - Read More…

Evans on Supreme Court DNA patent ruling

James Evans, MD, PhD, an international expert in gene patenting and genetics policy, comments on the June 13, 2013 Supreme Court ruling regarding gene patenting.

Evans on Supreme Court DNA patent ruling - Read More…

UNC scientists identify possible KRAS downstream target for pancreatic cancer therapy

UNC scientists identify possible KRAS downstream target for pancreatic cancer therapy

While the mutated KRAS oncogene is associated with many cancers, it has not yet been successfully targeted by a therapeutic agent. Scientists are trying to find another way to target the gene by blocking signals from another protein downstream.

UNC scientists identify possible KRAS downstream target for pancreatic cancer therapy - Read More…

Kim named to Society of Surgical Oncology Executive Council

Kim named to Society of Surgical Oncology Executive Council

HJ Kim, MD, associate professor in UNC’s division of surgical oncology and endocrinology, has been named as a member of the Society of Surgical Oncology's (SSO) Executive Council.

Kim named to Society of Surgical Oncology Executive Council - Read More…

Lucky 13 featured in video by UNC Endeavors

This summer, ten boy scouts from Chapel Hill are biking across the country to raise money for UNC Lineberger Comprehensive Cancer Center. For every $15,000 raised, UNC Lineberger has agreed to send one of their pediatric oncology patients to spend a week at Victory Junction, a camp for chronically ill children.

Lucky 13 featured in video by UNC Endeavors - Read More…

Single Fathers Due to Cancer in the media

The first of its kind program, Single Fathers Due to Cancer, continues to gain attention through media reports.

Single Fathers Due to Cancer in the media - Read More…

Remembering Dr. Keith Amos

UNC has lost a dear colleague. Dr. Keith Amos died suddenly in Edinburgh, Scotland, while on a Dr. Claude Organ, Jr., Travel Award from the American College of Surgeons. We all hold in our thoughts his wife, Ahaji, and their three young daughters.

Remembering Dr. Keith Amos - Read More…

UNC genetics researcher helps open Smithsonian exhibit

Clinical geneticist Jim Evans, MD, PhD helped to open the exhibition, Genome: Unlocking Life's Code. The high-tech, high-intensity display celebrates the 10th anniversary of production of the first complete human genome sequence also known as the genetic blueprint of the human body.

UNC genetics researcher helps open Smithsonian exhibit - Read More…

Kathy DeClue: A Second Chance to Say ‘I Do’

Kathy DeClue: A Second Chance to Say ‘I Do’

Kathy DeClue of Randolph County was featured in Family House Diaries in August 2012. She celebrated the success of a second stem cell transplant for leukemia by renewing her wedding vows with her husband of 41 years before 80 friends and family.

Kathy DeClue: A Second Chance to Say ‘I Do’ - Read More…

Coach Hatchell’s blueberry patch to support UNC Lineberger is ready for picking

UNC women’s basketball Coach Sylvia Hatchell’s blueberry patch near Black Mountain, NC is ready for the summer picking season.

Coach Hatchell’s blueberry patch to support UNC Lineberger is ready for picking - Read More…

Human and canine lymphomas share molecular similarities, first large-scale comparison shows

Humans and their pet dogs are close, so close that they both develop a type of cancer called diffuse large B-cell lymphoma. In humans it’s the most common lymphoma subtype while in dogs, it’s one of the most common cancers in veterinary oncology.

Human and canine lymphomas share molecular similarities, first large-scale comparison shows - Read More…

Yeh and Johnson awarded Lustgarten Foundation grant for pancreatic cancer

Yeh and Johnson awarded Lustgarten Foundation grant for pancreatic cancer

Jen Jen Yeh, MD, and Gary Johnson, PhD, were awarded a $326,708.00 grant from the Lustgarten Foundation for a one-year pilot study to investigate the kinome landscape of pancreatic cancer.

Yeh and Johnson awarded Lustgarten Foundation grant for pancreatic cancer - Read More…

Murine study predicts cancer drug responsiveness in human tumors

It’s a GEMM of a system. Genetically engineered mouse models that is. Using them allows scientists to study cancer in a way that more naturally mimics how human tumors exist within the complex environment of the body.

Murine study predicts cancer drug responsiveness in human tumors - Read More…

DeSimone - Research collaboration further customizes novel nanoparticles

Researchers at the University of North Carolina at Chapel Hill and MIT have combined two novel technologies to create specialized versions of tiny, coated nanoparticles. Through the use of a special coating technique, the researchers were further able to customize highly reproducible nanoparticles made using the PRINT platform created at UNC, which enables scientists to manufacture particles in a near-infinite array of shapes, sizes and material compositions. The combination of these unique technologies may result in developing more effective medicines, efficient electronics and technological advances in many other fields.

DeSimone - Research collaboration further customizes novel nanoparticles - Read More…

Cancer drug labels missing key information about patients’ symptoms

Cancer drug labels missing key information about patients’ symptoms

For patients facing treatment for cancer, it is essential to understand how their symptoms will be affected. Symptoms like pain, fatigue, or nausea can result from the cancer, or from treatment side effects. The best way to collect this information is from patients themselves in research studies. But almost no drug labels in the U.S. include this information. As a result, incomplete information is available to patients and clinicians to help with treatment decisions.

Cancer drug labels missing key information about patients’ symptoms - Read More…

Nurse Coordinators visit Good Morning America

Nurse Coordinators for the UNC Bone Marrow and Stem Cell Transplant Program show their support for Good Morning America anchor, Robin Roberts.

Nurse Coordinators visit Good Morning America - Read More…

Inhibiting Macrophage MerTK Signaling Creates an Innate Immune Response Against Cancer

The tyrosine kinase MerTK plays a prominent role in the body’s immune response. MerTK signaling helps “calm” the body’s first line of immunity, the macrophage, while it performs the routine duties - clearing cells that die and healing damaged tissue.

Inhibiting Macrophage MerTK Signaling Creates an Innate Immune Response Against Cancer - Read More…

Baldwin Receives Continued Support from Waxman Cancer Research Foundation

Baldwin Receives Continued Support from Waxman Cancer Research Foundation

Albert Baldwin, PhD, William Rand Kenan Professor of Biology and associate director of UNC Lineberger Comprehensive Cancer Center, has received a one-year continuation grant from the Samuel Waxman Cancer Research Foundation.

Baldwin Receives Continued Support from Waxman Cancer Research Foundation - Read More…

Outdated practice of annual cervical cancer screenings may cause more harm than good

For decades, women between the ages of 21 and 69 were advised to get annual screening exams for cervical cancer. In 2009, however, accumulating scientific evidence led major guideline groups to agree on a new recommendation that women be screened less frequently: every three years rather than annually.

Outdated practice of annual cervical cancer screenings may cause more harm than good - Read More…

Basch - National standards to evaluate health care quality based on how patients feel

Basch - National standards to evaluate health care quality based on how patients feel

National quality assessment programs usually measure and reward practices based on improving clinical processes such as re-hospitalization or infection rates. While this type of information is important and useful to clinicians, it doesn’t always take into account what is most important to the patient and families of the patient receiving care, such as the management of long-term symptoms or ability to conduct daily activities.

Basch - National standards to evaluate health care quality based on how patients feel - Read More…

Wheeler wins ACS grant to study racial disparities in breast cancer outcomes

Wheeler wins ACS grant to study racial disparities in breast cancer outcomes

Stephanie Wheeler, PhD, assistant professor of health policy and management at Gillings School of Global Public Health, will receive $727,000 over five years through an American Cancer Society Mentored Research Scholar Grant.

Wheeler wins ACS grant to study racial disparities in breast cancer outcomes - Read More…

Hayes-Wilkerson histology

Hayes-Wilkerson histology

Histological types are labeled by different colors in the clinical diagnosis and histology expression predictor tracks. Prediction confidence and stromal score are shaded green to white to blue indicating high to low values. The highest quality predictions exhibit high confidence and low stromal scores. - UNC/Hayes lab

Hayes-Wilkerson histology - Read More…

RNA Diagnostic Test from Paraffin Improves Lung Cancer Diagnosis Over Routine Microscopic Evaluation Alone

Knowing what type of lung cancer a patient has is critical to determine which drug will work best and which therapies are safest in the era of personalized medicine. Key to making that judgment is an adequate tumor specimen for the pathologist to determine the tumor’s histology, a molecular description of a tumor based on the appearance of cells under a microscope. But not all specimens are perfect, and are sometimes so complex that a definitive diagnosis presents a challenge.

RNA Diagnostic Test from Paraffin Improves Lung Cancer Diagnosis Over Routine Microscopic Evaluation Alone - Read More…

UNC Lineberger announces Marci Kramish Campbell Dissertation Award recipients

Shellie Ellis, MA, and Shelley Golden, PhD, of the Gillings School of Global Public Health are the 2013 recipients of the Marci Kramish Campbell Dissertation Award, a competitive $5,000 award to recognize excellence in dissertation research focused on cancer and the population sciences.

UNC Lineberger announces Marci Kramish Campbell Dissertation Award recipients - Read More…

Lamberth and Shirley Mitchell: Losing Teeth, but Keeping Spirit and Faith

A 65-year-old Person County man is successfully treated for a rare head and neck cancer, but the treatment side effects damaged his teeth and gums. He may have lost his pearly whites, but not his spirit or his faith.

Lamberth and Shirley Mitchell: Losing Teeth, but Keeping Spirit and Faith - Read More…

Baldwin discusses the role of NF-κB in cancer at OncLive

Albert Baldwin, PhD, Professor of Biology and Associate Director of Basic Research at UNC Lineberger discusses the regulation and biological functions of NF-κB in cancer at OncLive.

Baldwin discusses the role of NF-κB in cancer at OncLive - Read More…

Su awarded NIH grant to develop immune therapies for hepatitis B

Su awarded NIH grant to develop immune therapies for hepatitis B

The National Institute of Health has awarded University of North Carolina researcher Lishan Su, PhD, with a $2 million four-year R01 grant to investigate using a novel immune therapy to treat chronic hepatitis B virus (HBV) infection.

Su awarded NIH grant to develop immune therapies for hepatitis B - Read More…

Blues singer back on stage after chemo took his voice

WRAL features Bill McCulloch, known as Windy City Slim, a blues singer who learned to reclaim his voice after treatment from head and neck cancer caused his vocal muscles to atrophy.

Blues singer back on stage after chemo took his voice - Read More…

2013 UCRF Innovation Awards announced

UCRF Competitive Grants Program 2013 Innovation Awards were chosen from 51 applications. The awards provided $1,180,000 to support research among the six winners.

2013 UCRF Innovation Awards announced - Read More…

Sharpless aging research discussed in the New York Times

Sharpless aging research discussed in the New York Times

Research that developed a method of visualizing aging and tumor growth in mice by Norman Sharpless, MD, Wellcome Distinguished Professor of Cancer Research and Deputy Cancer Center Director, was featured in an article on biological markers of aging in the New York Times.

Sharpless aging research discussed in the New York Times - Read More…

Brian Burnham of Lucky 13 wins WCHL's Hometown Hero Award

Brian Burnham is an assistant scout master and one of the leaders of Troop 845's Lucky 13 Bike Trip, a fundraiser for UNC Lineberger.

Brian Burnham of Lucky 13 wins WCHL's Hometown Hero Award - Read More…

Human cells respond in healthy, unhealthy ways to different kinds of happiness

Human bodies recognize at the molecular level that not all happiness is created equal, responding in ways that can help or hinder physical health, according to new research led by Barbara L. Fredrickson, Kenan Distinguished Professor of psychology in the College of Arts and Sciences at the University of North Carolina at Chapel Hill.

Human cells respond in healthy, unhealthy ways to different kinds of happiness - Read More…