Seeking the patient voice early in the cessation process is critical to success.
A study by UNC Lineberger Comprehensive Cancer Center researchers led by Andrew Wang, MD, has been published in the journal Biomaterials. The study found that a nanoparticle formulation of histone deacetylase inhibitors is more effective in sensitizing solid tumor cells to radiation than small-molecule formations of the drug. Wang is a UNC Lineberger member, assistant professor in the UNC School of Medicine Department of Radiation Oncology and a member of the Carolina Institute of Nanomedicine and Carolina Center for Cancer Nanotechnology.
Hepatitis C virus infection is a common cause of liver disease and of liver cancer in the United States. Through a new study that explores one aspect of how the virus hijacks host cell machinery to replicate itself, UNC Lineberger Comprehensive Cancer Center researchers have gained insight into the workings of a potential drug target for hepatitis C.
Nathan Ladd thought he had sprained a groin muscle during his work with the Currituck Golf Club in Corolla, NC in May of 2006. Ice and Ibuprofen didn’t relieve the pain, and the 28-year-old noticed that his testicle was swollen and hard, so he went to a doctor.
When former school nurse Carol Enarson of Chapel Hill learned she had melanoma, she was shocked. After all, as a school nurse at Forsyth Country Day School (FCDS) in Winston-Salem she had developed innovative sun safety programs for elementary school students. “It is best to teach sun safety early on and before they start thinking about tanning beds,” she says.
Pam Kubacki says her survival is a miracle. In 1999 she underwent surgery to repair a hernia. Her doctor found problematic tissue during the procedure. After testing she was told that the tissue was not cancerous.
Barb Martin of Raleigh didn’t know that the advocacy work she did after earning her MPH degree from the UNC Gillings School of Global Public Health would help in her experience with breast cancer.
Charles McDonald knows firsthand what patients need. As a sickle cell patient and a prostate cancer survivor, he has learned how to be an advocate, how to take care of his health and how to heed his body’s warning signs that something may be wrong.
In 2003, Shirley Colagrossi, who had recently moved to Chapel Hill, had a mammogram. She had her medical records transferred so that her new mammogram could be compared to previous ones. The radiologist detected changes, and asked her to return for more tests. She then learned that, at 68, she had breast cancer.
Polly Hudson likes to say that she has cancer only every four months when she comes for her CT scans. “That’s the only time I want to think about it.”
Robert Johnson always has an annual physical exam and attends the prostate cancer screening offered at his local hospital. “African-American men are more susceptible to prostate cancer, so if I have a problem, I want to catch it early.”
Fayetteville resident Cathy Andrews felt the lump in her breast and immediately called her doctor. A mammogram and ultrasound later, she was escorted into another room to see the doctor. “When they start drawing and measuring, you know something is wrong,” she says.
Graphic and jewelry designer, Nancy Raasch of Chapel Hill accommodates her cancer and lives a full life. She explains, “I always say I have cancer on Thursdays since I go to clinic on Thursdays.” The rest of her time is spent making jewelry, gardening, reading, cooking and walking her dog.
Amber Vance, a young-adult cancer survivor living in Raleigh, is making a difference.
Wanda Wooten spends her Tuesdays as a hospital volunteer in oncology. In February of 2005, she was diagnosed with ovarian cancer and was treated here at UNC under the guidance of Dr. Linda Van Le.
Despite Jack Hyer’s 15 years of work with the American Cancer Society, his diagnosis of non-Hodgkin’s Lymphoma in May 2000 still came as a surprise.
A vivacious beauty pageant winner, LaTeacha Coleman, of Fayetteville, didn’t expect to find two lumps in her breast since the 25-year-old had no history of breast cancer in her family.
In 1991, Jason Huckaby was an active college student in his third year at NC State. The chemical engineering major and avid mountain biker thought he had pulled a muscle but the pain didn’t subside. He visited a student health physician who immediately referred him to a Raleigh hospital where he was diagnosed with Stage 1 seminoma, a type of testicular cancer. He underwent surgery and then radiation at a second Raleigh facility.
Nancy Graham, a member of the N.C. Cancer Hospital Patient and Family Advisory Board, says “this Board is a working Board, doing more and more to make a difference for the patients and families. We’re not a Board that sits and says hello to each other every two months. We’re actively involved in many aspects of the cancer hospital.”
For Rivka From and her daughters Carlye and Courtney, genetic testing at UNC provided them with “an opportunity to live an amazing life,” Rivka says.