UNC Lineberger News

Quest to understand Hepatitis C link with liver cancer receives $2.35 million boost

Quest to understand Hepatitis C link with liver cancer receives $2.35 million boost

Chapel Hill, NC – Does hepatitis C cause liver cancer due to inflammation associated with the disease, or does the virus interact with host cells in a different way to promote the development of cancer?

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Bae-Jump to serve on NCI's Gynecologic Cancer Steering Committee

Bae-Jump to serve on NCI's Gynecologic Cancer Steering Committee

Victoria Bae-Jump, MD, PhD will serve a two-year term as a junior investigator on the Gynecologic Cancer Steering Committee of the National Cancer Institute, a member institute of the National Institutes of Health.

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UNC study highlights diagnosis of lung cancer subtypes

UNC study highlights diagnosis of lung cancer subtypes

In the processes of treating most cancers, one of the key pieces of information is the appearance of the tumor under the microscope using a technique called light microscopy. In lung cancer, for example, the appearance of the tumor determines both which chemotherapies are safe and which chemotherapies are effective. In addition, tumor appearance also suggests which patients should be tested for mutations that can be targeted by some of the most effective and safest drugs on the market.

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Norman E. Sharpless, MD, appointed the Wellcome Distinguished Professor in Cancer Research

Norman E. Sharpless, MD, appointed the Wellcome Distinguished Professor in Cancer Research

Chapel Hill, NC – Norman E. “Ned” Sharpless, MD, professor of medicine and genetics and Associate Director for Translational Research at UNC Lineberger Comprehensive Cancer Center has been appointed the Wellcome Distinguished Professor in Cancer Research. The professorship was established by the School of Medicine in 1988 with gifts from the Burroughs Wellcome Fund and the William A. Smith Trust of Wadesboro, NC. The gifts were supplemented by the state of North Carolina the Distinguished Professors Endowment Trust Fund to create the endowed professorship.

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Grant to fund use of kinase test in HER2-positive breast cancer

Grant to fund use of kinase test in HER2-positive breast cancer

Chapel Hill, NC – Susan G. Komen for the Cure® has awarded a grant of almost $900,000 to Lisa A. Carey, MD, and Gary Johnson, PhD, to research clinical applications for the first broad-based test for protein kinase activation and response to inhibitory drugs in HER2-positive breast cancer.

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DNA replication protein also has a role in mitosis, cancer

DNA replication protein also has a role in mitosis, cancer

The finding presents a possible explanation for why so many cancers possess not just genomic instability, but also more or less than the usual 46 DNA-containing chromosomes.

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Study shows benefit of new maintenance therapy for multiple myeloma

Study shows benefit of new maintenance therapy for multiple myeloma

Chapel Hill, NC – Multiple myeloma is a form of cancer where the plasma cells in the bone marrow grow out of control, causing damage to bones as well as predisposing patients to anemia, infection and kidney failure. A medical procedure called autologous hematopoietic stem cell transplantation, commonly known as a stem cell transplant, is frequently an important treatment option for many patients.

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