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Dan Hollern, PhD, and Charles Perou, PhD

November 14, 2019

Findings could help identify which aggressive breast cancers will respond to immune treatments

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer. The U.S. Food and Drug Administration recently approved a treatment that combines an immunotherapy drug and chemotherapy for triple negative breast cancer, but …

Headshot of Antonio Amelio

November 5, 2019

Researchers use genetic insights to develop model for HPV-linked head and neck cancer

A University of North Carolina Lineberger Comprehensive Cancer Center-led research team has used genetic insights about head and neck cancers linked to HPV, or human papillomavirus, to improve laboratory tools for studying the disease. Leveraging their discovery that different subtypes of HPV-linked oropharyngeal squamous cell carcinoma exist based on the expression levels of two different …