Researchers identify strategy to block immunosupressive signals in melanoma

September 16, 2019

Cancer cells have a clever approach to avoid key immune cells intent on killing them. Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center report in the journal Cancer Immunology Research they have developed a strategy to shut down signals that keep cancer-killing immune cells from infiltrating melanoma. By blocking receptors on the … Continued

Can scientists predict which cancer markers are likely to trigger an immune response?

September 12, 2019

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have designed and validated a model for predicting what might make an effective cancer vaccine against a patient’s tumor. This finding could help overcome a significant obstacle in the development of personalized cancer vaccines. In a study published in the journal Cancer Immunology Research, … Continued

Leukemia & Lymphoma Society grant supports drug discovery research

September 3, 2019

The Leukemia & Lymphoma Society has awarded a $971,484 Screen to Lead grant to University of North Carolina Lineberger Comprehensive Cancer Center researchers to launch an investigation of new drug compounds that would block enzymes that can become hyperactive in blood cancer cells when mutated. UNC Lineberger’s John Sondek, PhD, a professor in the UNC … Continued

UNC Lineberger’s Bryant, Haley develop oncology nursing leaders in Malawi

August 27, 2019

UNC Lineberger’s Ashley Leak Bryant, PhD, RN-BC, OCN, and clinical oncology nurse Jen Haley, MSN, RN, CNL, have a passion for developing future leaders of oncology nursing, not just in North Carolina, but globally. Bryant and Haley have been part of an effort to build the oncology nursing workforce in Malawi, a country in sub-Saharan … Continued

Amelio named top recipient of 2019 IADR Joseph Lister Award for New Investigators

August 26, 2019

UNC Lineberger’s Antonio Amelio, PhD, assistant professor in the UNC Adams School of Dentistry, was named the first place recipient of the 2019 IADR Joseph Lister Award for New Investigators. The award is managed by the International Association for Dental Research (IADR), and supported by Johnson & Johnson Consumer Inc., makers of Listerine. The competition … Continued

Wang leads study published in Advanced Science

August 26, 2019

UNC Lineberger’s Andrew Z. Wang, MD, an associate professor in the UNC School of Medicine Department of Radiation Oncology, was corresponding author of a paper published in Advanced Science. The study reported on the development of a “nanopatch” to prevent postsurgical adhesion, which is when scar tissue joins two different tissues after surgery. They reported … Continued

E-cigs can trigger same lung changes seen in smokers, emphysema

August 22, 2019

E-cigarette “vaping” is widely assumed to be safer than cigarette smoking, but scientists at the University of North Carolina have uncovered evidence suggesting that vaping promotes the same cellular responses found in smokers with emphysema. In a study published in the American Journal of Respiratory and Critical Care Medicine, the UNC scientists found that the lungs of vapers … Continued

Researchers develop method for identifying aggressive breast cancer drivers

August 13, 2019

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method to precisely identify individual … Continued