About the Carolina Endometrial Cancer Study

The Carolina Endometrial Cancer Study (CECS) is a population-based study of endometrial cancer that is being conducted statewide in North Carolina in conjunction with the Central Cancer Registry. Our goal is to enroll about 1,800 adults (age 20–80) living in North Carolina (all 100 counties) at the time of their recent first diagnosis of endometrial cancer to learn more about survivorship after endometrial cancer and why some people have different outcomes and experiences.

The CECS explores survivorship and experiences after endometrial cancer. Our goal is to understand more about factors that contribute to different outcomes among adults with endometrial cancer, including tumor recurrence, survival, and quality of life changes. Our team investigates factors such as tumor biology, lifestyle and behaviors, socioeconomic backgrounds, and barriers to care. We will examine these factors in a diverse cohort of adults diagnosed with endometrial cancer across North Carolina.

Participants will be asked to complete a baseline survey, consent to obtain medical records, a sample of stored tissue from diagnosis/treatment of endometrial cancer, and provide a saliva sample through a self-collection kit. Our participants will be contacted for follow-up for about 5 years in order to obtain updated treatment and outcomes information.

The Carolina Endometrial Cancer Study (CECS) is funded by the University Cancer Research Fund of North Carolina and the National Institutes of Health (U01CA281026). CECS recruits participants with the assistance of Rapid Case Ascertainment (RCA), a collaboration between the North Carolina Central Cancer Registry and the University of North Carolina Lineberger Comprehensive Cancer Center supported by P30CA016086 and the University Cancer Research Fund of North Carolina. The findings and conclusions herein are those of the author(s) and do not necessarily represent the views of the North Carolina Department of Health and Human Services, Division of Public Health. We are grateful to CECS participants and study staff.