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Dan Hollern, PhD, and Charles Perou, PhD

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer. The U.S. Food and Drug Administration recently approved a treatment that combines an immunotherapy drug and chemotherapy for triple negative breast cancer, but …

Brian Strahl, PhD, is a UNC Lineberger member and professor of biochemistry and biophysics in the UNC School of Medicine

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments. In a study published in Molecular Cell, the scientists found that a chemical mark on histones – a key protein involved in the function of our …

A University of North Carolina Lineberger Comprehensive Cancer Center-led research team has used genetic insights about head and neck cancers linked to HPV, or human papillomavirus, to improve laboratory tools for studying the disease. Leveraging their discovery that different subtypes of HPV-linked oropharyngeal squamous cell carcinoma exist based on the expression levels of two different …

UNC Lineberger's Timothy Gershon, MD, PhD, and Jennifer Ocasio, PhD, who identified a possible approach to blocking medulloblastoma brain tumor

UNC Lineberger researchers have identified a potential approach to stop the growth of medulloblastoma, the most common type of brain tumor in children.

A dense web of tissue can surround pancreatic cancer tumors, impeding treatment and sometimes acting as a barrier to the tumor’s spread. Jen Jen Yeh, MD, and colleagues have published a paper in Nature Communications that demonstrates their novel approach to distinguishing cancerous tissue from the surrounding connective tissue and stromal cells as well as from immune cells in the tumor’s environment in order to drive personalized treatment strategies.

The National Cancer Institute has awarded a four-year, more than $1.87 million grant to University of North Carolina Lineberger Comprehensive Cancer Center researchers to study the impact of implementing financial navigation services at five rural cancer centers in North Carolina to help patients cope with the financial burden, or financial toxicity, related to cancer care. …

Recipients of the 2019 Oncology Excellence Awards

Five members of the North Carolina Cancer Hospital team were recognized at the 2019 UNC Oncology Excellence Awards ceremony on Thursday, Oct. 3. The awards honor oncology nurses, allied health professionals, and administrative staff for exceptional care of and devotion to individuals with cancer and their families and to the oncology profession. Celebrated annually since …

Adam Goldstein, MD, MPH, is a UNC Lineberger member and professor in the UNC School of Medicine Department of Family Medicine.

The National Cancer Institute has awarded University of North Carolina Lineberger Comprehensive Cancer Center researcher Adam Goldstein, MD, MPH, a five-year, $2.7 million grant to develop more effective health warnings for little cigars and cigarillos. Nearly 12 million U.S. adults reported smoking cigars within a single month, according to 2016 national survey, and little cigars …

The National Cancer Institute has awarded a three-year, $1.4 million grant to University of North Carolina Lineberger Comprehensive Cancer Center researcher Seth M. Noar, PhD, to conduct studies that will help improve the effectiveness of tobacco prevention advertisements for adolescents. Specifically, Noar and his collaborators will develop new metrics to gauge the effectiveness of tobacco …

UNC Lineberger researchers published new findings in Nature Communications that help explain one path that breast cancers can take as they leave tumors and spread throughout the body.

Tag: Home News

Findings could help identify which aggressive breast cancers will respond to immune treatments

Feast or famine: Scientists find key bio ‘switch’ that helps cells adapt

Researchers use genetic insights to develop model for HPV-linked head and neck cancer

Researchers identify possible approach to block medulloblastoma growth

Researchers develop method for separating tissue types in tumor samples

NCI grant to help patients navigate costs of cancer care

2019 Oncology Excellence Awards celebrate compassionate nurses and staff

Goldstein to use $2.7M NCI grant to develop, test warnings for little cigars, cigarillos

NCI awards Noar $1.4M to measure impact of tobacco prevention advertisements

Findings help explain how breast cancer can spread in the body