Findings could help identify which aggressive breast cancers will respond to immune treatments

November 14, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer. The U.S. Food and Drug Administration recently approved a treatment that combines an immunotherapy drug and chemotherapy for triple negative breast cancer, but … Continued

Feast or famine: Scientists find key bio ‘switch’ that helps cells adapt

November 5, 2019

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments. In a study published in Molecular Cell, the scientists found that a chemical mark on histones – a key protein involved in the function of our … Continued

Researchers use genetic insights to develop model for HPV-linked head and neck cancer

November 5, 2019

A University of North Carolina Lineberger Comprehensive Cancer Center-led research team has used genetic insights about head and neck cancers linked to HPV, or human papillomavirus, to improve laboratory tools for studying the disease. Leveraging their discovery that different subtypes of HPV-linked oropharyngeal squamous cell carcinoma exist based on the expression levels of two different … Continued

Researchers identify possible approach to block medulloblastoma growth

October 23, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children. UNC Lineberger’s Timothy Gershon, MD, PhD and colleagues reported in the journal Development that by blocking a signal called GSK-3, they could control tumor growth in a … Continued

Researchers develop method for separating tissue types in tumor samples

October 21, 2019

A dense web of tissue can surround pancreatic cancer tumors, impeding treatment and sometimes acting as a barrier to the tumor’s spread. Researchers want to distinguish cancerous tissue from the surrounding connective tissue and cells known as stroma as well as from immune cells in the tumor’s environment in order to drive personalized treatment strategies. … Continued

NCI grant to help patients navigate costs of cancer care

October 14, 2019

The National Cancer Institute has awarded a four-year, more than $1.87 million grant to University of North Carolina Lineberger Comprehensive Cancer Center researchers to study the impact of implementing financial navigation services at five rural cancer centers in North Carolina to help patients cope with the financial burden, or financial toxicity, related to cancer care. … Continued

2019 Oncology Excellence Awards celebrate compassionate nurses and staff

October 8, 2019

Five members of the North Carolina Cancer Hospital team were recognized at the 2019 UNC Oncology Excellence Awards ceremony on Thursday, Oct. 3. The awards honor oncology nurses, allied health professionals, and administrative staff for exceptional care of and devotion to individuals with cancer and their families and to the oncology profession. Celebrated annually since … Continued

Goldstein to use $2.7M NCI grant to develop, test warnings for little cigars, cigarillos

October 7, 2019

The National Cancer Institute has awarded University of North Carolina Lineberger Comprehensive Cancer Center researcher Adam Goldstein, MD, MPH, a five-year, $2.7 million grant to develop more effective health warnings for little cigars and cigarillos. Nearly 12 million U.S. adults reported smoking cigars within a single month, according to 2016 national survey, and little cigars … Continued