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Headshot of Barbara Savoldo

December 6, 2019

UNC Lineberger researchers to share data, expertise at 61st ASH Annual Meeting

University of North Carolina Lineberger Comprehensive Cancer Center researchers will be well-represented at the 61st American Society of Hematology Annual Meeting in Orlando, Florida, Dec. 7-10. ASH is the world’s largest professional society of hematologists and is dedicated to understanding, diagnosing, treating and preventing blood disorders. The society expects more than 20,000 hematologists and health …

July 12, 2019

Scientists publish overview of the latest in cancer vaccine target research

University of North Carolina Lineberger Comprehensive Cancer Center researchers have published a review of experimental cancer vaccines that identified areas of promise and challenges for the field. In the Nature Reviews Cancer, researchers outlined current research into targets for therapeutic cancer vaccines, an area of active investigation focused on boosting immune responses to cancer. “Generally, …

Andrew Wang and Jonathan Serody

December 3, 2018

Wang and Serody awarded $2M grant to study personalized cancer vaccines

The University of North Carolina System recently awarded UNC Lineberger’s Andrew Wang, MD, and Jonathan Serody, MD, a four year, $2.09 million Research Opportunities Initiative grant to support their research using pharmacoengineering approaches to develop more effective personalized cancer vaccines. The grant was one of 15 awarded to scientists across the UNC System, with the specific intent to support …

Jonathan Serody, MD, UNC Lineberger member and the Elizabeth Thomas Professor in the UNC School of Medicine

August 21, 2017

Study sheds light on why some breast cancers have limited response to immunotherapy

Jonathan Serody, MD, Benjamin Vincent, MD, and a team of UNC Lineberger investigators published findings in the Journal of Clinical Investigation that may explain why drugs designed to unleash the immune system against cancer were ineffective in treating a type of triple negative breast cancer. They determined “claudin-low” tumors were releasing a chemical signal to attract regulatory T-cells, which prevented the immune system from rejecting the cancer.