Pancreatic Cancer Clinical Program Archives - Page 4 of 7

The KRAS gene is commonly mutated in cancer. In the journal Cancer Discovery, researchers led by Channing Der, PhD, and Aaron Hobbs, PhD, reported details of the role of the KRAS G12R mutation in pancreatic cancer, and therapeutic strategies that might work for this mutation type. By studying unique differences in DNA mutations within the same gene, researchers are working to uncover the mutation-specific mechanisms that drive cancerous growth.

A dense web of tissue can surround pancreatic cancer tumors, impeding treatment and sometimes acting as a barrier to the tumor’s spread. Jen Jen Yeh, MD, and colleagues have published a paper in Nature Communications that demonstrates their novel approach to distinguishing cancerous tissue from the surrounding connective tissue and stromal cells as well as from immune cells in the tumor’s environment in order to drive personalized treatment strategies.

UNC Lineberger’s Joseph G. Ibrahim, PhD, Alumni Distinguished Professor in the UNC Gillings School of Global Public Health Department of Biostatistics and director of the UNC Lineberger Biostatistics Core, and Jen Jen Yeh, MD, professor of pharmacology and surgery in the UNC School of Medicine, and vice chair for research in the Department of Surgery …

The U.S. Army has awarded a $559,799 grant to UNC Lineberger Comprehensive Cancer Center researcher Yuliya Pylayeva-Gupta, PhD, to investigate the role of the immune system in promoting pancreatic cancer’s spread.

Kirsten Bryant, PhD, is honored as one of three recipients of the Joseph S. Pagano Award, which recognizes outstanding work by the cancer center’s postdoctoral research associates.

UNC Lineberger’s Channing Der, PhD, Kenan Distinguished Professor in the UNC School of Medicine Department of Pharmacology, was corresponding author of a paper published in Science Signaling. The study identified a potential therapeutic target for patients with KRAS-mutant pancreatic ductal adenocarcinoma. Der and his colleagues described in the paper the use of a screening strategy …

The National Cancer Institute has awarded a grant for more than $2.2 million across five years to UNC Lineberger’s Yuliya Pylayeva-Gupta, PhD, to support her research into the immune response in pancreatic cancer, one of the deadliest cancers.

Tag: Pancreatic Cancer Clinical Program

Researchers find KRAS gene mutation differences have implications for pancreatic cancer treatment

Researchers develop method for separating tissue types in tumor samples

UNC Lineberger researchers published in Journal of the American Statistical Association

U.S. Army awards grant to Pylayeva-Gupta for study of immune system in pancreatic cancer

Researcher recognized for perseverance that led to study, plans for trials in pancreatic cancer

Der leads study published in Science Signaling

NCI awards $2.2M to Pylayeva-Gupta to investigate immune responses in pancreatic cancer

OncLive: Adjuvant Treatment Strategy Shows Promise in Pancreatic Cancer

NBC News: Improved detection and treatment of pancreatic cancer provides hope

Medical News Today: Pancreatic cancer: Two-hit treatment approach shows promise