January 16, 2020
Teaming up in the lab and in life: researchers make an impact on cancer science
Yuliya Pylayeva-Gupta, PhD, and Gaorav Gupta, MD, PhD, use their natural curiosity and drive to tackle cancer through their research at UNC Lineberger.
Tag: Pancreatic Cancer Clinical Program
January 9, 2020
Pancreatic cancer patient beats the odds to thrive after diagnosis
The care team at UNC Lineberger helped Mary Gillam beat the odds and become a pancreatic cancer survivor. “I truly could not have gotten through this without Chapel Hill’s support,” she said. “The whole team has been outstanding.”
November 26, 2019
Der named AAAS Fellow
The honor recognizes Der's contributions to cancer research. His lab's recent findings on pancreatic cancer have led to clinical studies of a new treatment.
November 21, 2019
Pancreatic cancer tumor classification could optimize treatment choices
In Clinical Cancer Research, a journal of the American Association for Cancer Research, Jen Jen Yeh, MD, and Naim Rashid, PhD, reported findings for how two subtypes of pancreatic cancer respond to treatments differently. Importantly, they found that one subtype of the disease showed poor responses to common therapies and also had worse survival outcomes.
November 18, 2019
Researchers find KRAS gene mutation differences have implications for pancreatic cancer treatment
The KRAS gene is commonly mutated in cancer. In the journal Cancer Discovery, researchers led by Channing Der, PhD, and Aaron Hobbs, PhD, reported details of the role of the KRAS G12R mutation in pancreatic cancer, and therapeutic strategies that might work for this mutation type. By studying unique differences in DNA mutations within the same gene, researchers are working to uncover the mutation-specific mechanisms that drive cancerous growth.
October 21, 2019
Researchers develop method for separating tissue types in tumor samples
A dense web of tissue can surround pancreatic cancer tumors, impeding treatment and sometimes acting as a barrier to the tumor’s spread. Jen Jen Yeh, MD, and colleagues have published a paper in Nature Communications that demonstrates their novel approach to distinguishing cancerous tissue from the surrounding connective tissue and stromal cells as well as from immune cells in the tumor’s environment in order to drive personalized treatment strategies.
October 21, 2019
UNC Lineberger researchers published in Journal of the American Statistical Association
UNC Lineberger’s Joseph G. Ibrahim, PhD, Alumni Distinguished Professor in the UNC Gillings School of Global Public Health Department of Biostatistics and director of the UNC Lineberger Biostatistics Core, and Jen Jen Yeh, MD, professor of pharmacology and surgery in the UNC School of Medicine, and vice chair for research in the Department of Surgery …
September 23, 2019
U.S. Army awards grant to Pylayeva-Gupta for study of immune system in pancreatic cancer
The U.S. Army has awarded a $559,799 grant to UNC Lineberger Comprehensive Cancer Center researcher Yuliya Pylayeva-Gupta, PhD, to investigate the role of the immune system in promoting pancreatic cancer’s spread.
September 6, 2019
Researcher recognized for perseverance that led to study, plans for trials in pancreatic cancer
Kirsten Bryant, PhD, is honored as one of three recipients of the Joseph S. Pagano Award, which recognizes outstanding work by the cancer center’s postdoctoral research associates.
August 13, 2019
Der leads study published in Science Signaling
UNC Lineberger’s Channing Der, PhD, Kenan Distinguished Professor in the UNC School of Medicine Department of Pharmacology, was corresponding author of a paper published in Science Signaling. The study identified a potential therapeutic target for patients with KRAS-mutant pancreatic ductal adenocarcinoma. Der and his colleagues described in the paper the use of a screening strategy …