July 26, 2019
Tag: Virology Research Program
July 22, 2019
Researchers unveil experimental compound to block therapeutic target in blood cancer
Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer. They also developed an experimental therapeutic to block the signal and slow tumor growth. In the journal Proceedings of the National Academy of Sciences, the researchers reported they have identified a …
April 25, 2019
Celebrating DNA
Today is National DNA Day, which commemorates the publication of the first scientific papers to explain the structure of DNA in 1953. In the cell, DNA is never alone. It is always complexed with proteins that help replicate the genetic code, to generate RNA – the language of proteins – or help the DNA combine …
February 19, 2019
Virus linked to cancer takes over ‘cellular mail’ to alter tumor environment
A virus linked to cancer can hijack the host’s cellular mail and could help drive changes in the environment around tumors, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found. A study published in PLOS Pathogens reports the Kaposi sarcoma-associated herpes virus can commandeer a mail system that host cells use to …
December 17, 2018
2018 UNC-Duke Viral Oncology & AIDS Malignancy Symposium poster competition winners announced
The UNC Lineberger Comprehensive Cancer Center virology and global oncology programs, in conjunction with the Duke Cancer Institute, hosted the 2018 UNC-Duke Viral Oncology & AIDS Malignancy Symposium at the Carolina Club on Dec. 13.
May 3, 2018
UNC Lineberger’s Griffith elected into National Academy of Sciences
UNC Lineberger's Jack Griffith, PhD, has conducted extensive research utilizing high-resolution electron microscopy to visualize protein-DNA interactions. He was elected into the National Academy of the Sciences, which is considered one of the highest scientific honors in the United States.
February 12, 2018
HIV exports viral protein in cellular packages
A study from the lab of UNC Lineberger's Dirk Dittmer, PhD, found that HIV sends out a protein called Nef in cellular packages called exosomes.
June 24, 2016
Cancer-causing virus mimics host signal to drive cell growth, protein production
UNC Lineberger researcher Blossom Damania, PhD, postdoctoral researcher Aadra Bhatt, PhD, and colleagues have discovered a slick trick a virus uses to spur cancerous cell growth in its host: the virus initiates a signal that mimics one of the host cell’s own signals.
![Malawian pathologist George Liomba was recruited to work with UNC-Project Malawi in Lilongwe. [Photo Credit: Dirk Dittmer, PhD, a UNC Lineberger member and co-director of the UNC Lineberger Global Oncology Program]](https://unclineberger.org/wp-content/uploads/sites/867/2018/10/filling-the-gap-image2-600x400.jpeg)
August 31, 2015
Filling the gap
In Malawi’s capital city, one pathologist has played an important role in speeding cancer diagnoses and supporting cancer research.
July 21, 2015
Researchers make discovery of how cancer-causing virus evades early immune response
In a study published today in the journal Proceedings of the National Academy of Sciences, UNC Lineberger researchers report findings of how Kaposi’s sarcoma-associated herpesvirus, or KSHV, can inhibit a signaling pathway involved in triggering part of the early immune response to the virus.