September 7, 2017
Academics and policymakers are using the Cancer Information & Population Health Resource, or CIPHR, to knit together data from multiple public and private sources to examine a wide range of complex issues tied to improving cancer outcomes in North Carolina.
August 21, 2017
Jonathan Serody, MD, Benjamin Vincent, MD, and a team of UNC Lineberger investigators published findings in the Journal of Clinical Investigation that may explain why drugs designed to unleash the immune system against cancer were ineffective in treating a type of triple negative breast cancer. They determined “claudin-low” tumors were releasing a chemical signal to attract regulatory T-cells, which prevented the immune system from rejecting the cancer.
August 1, 2017
William Y. Kim, MD, has published a study in JCO Precision Oncology that uncovered possible treatment approaches for urachal adenocarcinoma, a rare bladder cancer.
July 26, 2017
The Carolina Cancer Screening Initiative, led by Daniel S. Reuland, MD, MPH, brings together UNC Lineberger’s clinicians and public health researchers with community partners to implement evidence-based cancer screening programs to reduce cancer burden among North Carolinians.
June 26, 2017
In the journal Nature Nanotechnology, UNC Lineberger researchers led by Andrew Wang, MD, report on strides made in the development of a strategy to improve the immune system's detection of cancer proteins by using “sticky” nanoparticles.
June 8, 2017
UNC Lineberger member William Y. Kim, MD, and his colleagues report in the journal Nature Communications they have created laboratory models of both papillary and clear cell renal cell carcinoma that faithfully mimic the genetic changes seen in tumors of patients with these cancers.
May 30, 2017
Founded with support from KickStart Venture Services, a UNC-Chapel Hill program that works to turn University research into new companies, G1 Therapeutics is developing novel therapeutics based on discoveries at UNC Lineberger Comprehensive Cancer Center.
May 12, 2017
UNC Lineberger's Michael J. Emanuele, PhD, and colleagues have identified a key activator that can turn on FoxM1, a protein that drives expression of genes that help cells replicate and divide, a finding they published in the journal Molecular and Cellular Biology. They also discovered, paradoxically, that the activator for FoxM1 is also responsible for turning this protein off.
May 2, 2017
In a pair of preclinical studies published in the journal Neuro-Oncology, UNC Lineberger's C. Ryan Miller, MD, PhD, and the Phoenix-based Translational Genomics Research Institute report on the genetic evolution of glioblastoma as it progresses in severity and a potential strategy to treat this often fast-growing brain cancer type.
May 1, 2017
In findings published in the journal Cancer, Epidemiology, Biomarkers & Prevention, UNC Lineberger Comprehensive Cancer Center researchers confirmed the link between alcohol consumption and breast cancer risk in a study in black women. The association has been seen in other studies drawn from majority white populations.
