Researchers publish milestone review on the role of cell signaling proteins in cancer

January 29, 2019

University of North Carolina Lineberger Comprehensive Cancer Center scientist Antonio “Tony” Amelio, PhD, is not necessarily looking for the “smoking gun” of cancer biology, or one single cause of cancer. Instead, he’s looking into how a family of newly described proteins involved in the cellular stress response can cause a complex ripple effect of changes … Continued

Scientists train a computer to classify breast cancer tumors

November 19, 2018

Using technology similar to the type that powers facial recognition on a smartphone, Charles M. Perou, PhD, Melissa Troester, PhD, and Heather D. Couture have trained a computer to analyze breast cancer images and then classify the tumors with high accuracy.

HPV blood test shows promise for tracking head and neck cancer after treatment

October 23, 2018

UNC Lineberger’s Bhishamjit S. Chera, MD, will present preliminary findings at the 60th Annual Meeting of the American Society for Radiation Oncology on Tuesday from a study that evaluated a blood test for HPV-linked oropharyngeal squamous cell carcinoma, which is a cancer of the back of the throat. The findings demonstrated the test could be an effective and less costly alternative for monitoring for cancer recurrence after radiation treatment.

Scientists zero in on ways to boost colorectal cancer screening

October 15, 2018

UNC Lineberger’s Daniel Reuland, MD, MPH, and colleagues published in JAMA Internal Medicine a review of data from 73 randomized clinical trials that tested different ways of increasing screening for colorectal cancer. Their analysis identified three approaches as being the most effective.

Breaking the link between obesity, gastrointestinal cancers

September 26, 2018

In an article in the journal Nature Reviews Gastroenterology & Hepatology, UNC Lineberger’s Stephen Hursting, PhD, MPH, and his colleagues reviewed findings from research looking at the biological links between obesity and cancers of the colon, rectum, pancreas, liver, esophagus, gallbladder and stomach, as well as published studies on how diet, exercise, weight loss surgery, and other weight-related interventions may help reverse this connection.