UCRF Archives - UNC Lineberger

Ewing's sarcoma that has metastasized to the pleura fluid.

Pengda Liu, PhD, and colleagues have created a small molecule that targets and breaks down a protein linked to Ewing sarcoma, an aggressive cancer that mostly affects children and teens.

Human cells with acute myelocytic leukemia (AML) in the pericardial fluid, shown with an esterase stain at 400x magnification.

UNC Lineberger researchers have demonstrated a faster, more cost-effective approach to analyzing the genetic makeup of pediatric acute leukemia. Determining a cancer’s genomic classification is critical to developing a more effective treatment plan tailored to a patient’s tumor.

Scientific illustration of a CAR-T cell attacking a cancer cell.

Gianpietro Dotti, MD, and colleagues report in Nature Immunology they have identified a cocktail of three different drugs that can be used to generate more robust CAR-Ts to fight cancer.

A clinical staff talks with a soldier in a clinic exam room.

UNC Lineberger is leading an innovative cancer prevention partnership at Fort Bragg that is designed to reduce tobacco use and promote HPV vaccination.

A woman holds a stamped, padded mailer envelope.

Previous research has shown this kind of intervention is effective in large, integrated health systems. However, its impact was unknown in federally qualified health centers and the patient populations they serve.

William Kim, MD, and Tracy Rose, MD, MPH, published a review highlighting new scientific insights that have led to advances in kidney cancer treatment and increased survival rates.

Exteriors of the UNC Lineberger and Marsico Hall buildings.

More than $1.3 million in UNC Lineberger developmental research grants were awarded to 13 faculty members and one postdoctoral trainee this spring.

Headshots of Rihe Liu, Jenny Ting, and Sirui Li.

UNC Lineberger researchers have developed a molecule that is much more effective than a previously identified molecule at activating a biological pathway and spurring a strong anti-cancer immune response in preclinical studies.

A person wearing PPE looking into a microscope.

UNC Lineberger researchers are using CAR-T to create better and personalized cancer treatments in one of the largest cell therapy facilities on the East Coast.

Tag: UCRF

Researchers develop molecule that targets Ewing sarcoma

Adaptive whole-genome sequencing could transform childhood leukemia diagnosis

Three drug cocktail shows potential to boost CAR-T cancer therapy

Improving health of military personnel and families through collaboration, research

Cancer Letter: Home testing kits, coordinated outreach improve CRC screening rates

Home testing kits and coordinated outreach substantially improve colorectal cancer screening rates

Kim, Rose highlight advances in kidney cancer research and care in JAMA

UNC Lineberger provides $1.3 million in developmental research grants

Newly engineered molecule bypasses toxicity previously found in key cancer-fighting pathway

Curated cancer care