UCRF Archives - UNC Lineberger

Patients using smartphones, tablets and laptops to report symptoms.

Digital reporting technologies created by UNC Lineberger researchers are now being used in North Carolina and across the country to improve care and outcomes for cancer patients.

UNC Lineberger's Lisa Carey and Chuck Perou.

UNC Lineberger researchers are leading next-generation clinical breast cancer trials as part of a national project using cutting-edge technologies to track tumor changes in real time.

Chad Pecot, MD, and Kristina Whately, PhD, work in the Pecot Lab.

Chad Pecot, MD, leads cancer RNA research at UNC Lineberger, creating innovative therapies and promising treatment strategies for multiple cancer mutations.

Single strand ribonucleic acid, RNA research and therapy.

Chad Pecot, MD, and colleagues have demonstrated that a uniquely engineered drug that zeroes in on a mutated gene called KRAS G12V could potentially stop KRAS-dependent cancers in their tracks.

Michael Emanuele, PhD, and colleagues have discovered that an enzyme called USP37 plays a crucial role in ensuring our cells copy their DNA correctly.

Ewing's sarcoma that has metastasized to the pleura fluid.

Pengda Liu, PhD, and colleagues have created a small molecule that targets and breaks down a protein linked to Ewing sarcoma, an aggressive cancer that mostly affects children and teens.

Human cells with acute myelocytic leukemia (AML) in the pericardial fluid, shown with an esterase stain at 400x magnification.

UNC Lineberger researchers have demonstrated a faster, more cost-effective approach to analyzing the genetic makeup of pediatric acute leukemia. Determining a cancer’s genomic classification is critical to developing a more effective treatment plan tailored to a patient’s tumor.

Scientific illustration of a CAR-T cell attacking a cancer cell.

Gianpietro Dotti, MD, and colleagues report in Nature Immunology they have identified a cocktail of three different drugs that can be used to generate more robust CAR-Ts to fight cancer.

A clinical staff talks with a soldier in a clinic exam room.

UNC Lineberger is leading an innovative cancer prevention partnership at Fort Bragg that is designed to reduce tobacco use and promote HPV vaccination.

Tag: UCRF

Building tools to help doctors better track patient symptoms, improve outcomes

UNC Lineberger continues its national leadership in breast cancer research

‘If you’re trying to make a difference in cancer, you can’t go slow’

Uniquely engineered KRAS-targeted cancer drug found to be effective in early studies

UNC researchers discover an enzyme that protects DNA during rapid cell divisions

Researchers develop molecule that targets Ewing sarcoma

Adaptive whole-genome sequencing could transform childhood leukemia diagnosis

Three drug cocktail shows potential to boost CAR-T cancer therapy

Improving health of military personnel and families through collaboration, research

Cancer Letter: Home testing kits, coordinated outreach improve CRC screening rates