SPORE Cores
UNC Breast Cancer SPORE Cores
Administrative Core
The Administrative Core supports an exceptional team of breast cancer translational researchers who are exploring approaches to convert basic science discoveries into new and more effective breast cancer treatments.
The Administrative Core provides scientific, administrative and financial oversight of all components of the UNC Breast Cancer SPORE. This includes coordinating input from leadership, advocates, and the External Advisory Board, with the objective of monitoring, evaluating, and supporting SPORE major and pilot projects, recruitment, career enhancement, and mentoring, and facilitating interactions with the NCI SPORE program and other NCI SPOREs.
Biostatistics & Bioinformatics Core
The Biostatistics & Bioinformatics Core, led by faculty geneticists, statisticians, and biostatisticians, provides support for statistical and bioinformatics analysis of complex data sets and utilizes existing shared resources supported by the UNC Lineberger Comprehensive Cancer Center.
It is an integral partner with each project. Complementary skills possessed by the Biostatistics & Bioinformatics Core faculty support the application and development of approaches for to cross-platform data integration and high-dimensional biomarker discovery to optimize clinical decision-making.
Pathology and Immunobiology Core
The Pathology and Immunobiology Core supports all projects by providing a coordinated, quality-controlled, quality-assured facility for the procurement, processing, storage, and distribution of human biologic specimens.
Specifically, it provides centralized tissue and specimen banking, receipt and processing of breast-related human specimens, including: freshly procured, snap-frozen and formalin-fixed paraffin embedded block specimens, preparation of tissue microarrays, cell microarrays, morphological evaluation and morphology-based assays, assay development and training, immunogenetics, flow-cytometry, and digital imaging and image analysis for spatial quantification of molecular analytes in intact specimens.
