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Gianpietro Dotti and Yang Xu

February 3, 2020

Researchers develop method to engineer immune cells so they grow even in hostile tumors

Tumors can create a hostile environment for cancer-fighting immune cells. In a new study, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method for engineering immune cells to improve their survival and proliferation, even within a hostile tumor. Researchers led by UNC Lineberger’s Gianpietro Dotti, MD, report in the journal Nature …

Gianpietro Dotti and Peishun Shou

January 30, 2020

UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells

A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects. In a study published in Cancer Cell, researchers led by UNC Lineberger’s Gianpietro Dotti, …