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Gianpietro Dotti and Yang Xu

February 3, 2020

Researchers develop method to engineer immune cells so they grow even in hostile tumors

Tumors can create a hostile environment for cancer-fighting immune cells. In a new study, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method for engineering immune cells to improve their survival and proliferation, even within a hostile tumor. Researchers led by UNC Lineberger’s Gianpietro Dotti, MD, report in the journal Nature …

Headshot of Antonio Amelio

November 5, 2019

Researchers use genetic insights to develop model for HPV-linked head and neck cancer

A University of North Carolina Lineberger Comprehensive Cancer Center-led research team has used genetic insights about head and neck cancers linked to HPV, or human papillomavirus, to improve laboratory tools for studying the disease. Leveraging their discovery that different subtypes of HPV-linked oropharyngeal squamous cell carcinoma exist based on the expression levels of two different …