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2022

Jun Wang, PhD (Department of Biochemistry & Biophysics)

Wang, J., et al. EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis. Published Feb. 2022 in Nature Cell Biology (https://doi.org/10.1038/s41556-022-00850-x)

2021

Han Guo, PhD (Department of Genetics)

Guo, H., et al. Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites. Published Oct. 2020 in Science (https://doi.org/10.1126/science.aay9097)

Christine Roden, PhD (Department of Biology)

Iserman, C., Roden, C.A., et al. Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Published Nov. 2020 in Molecular Cell (https://doi.org/10.1016/j.molcel.2020.11.041)

Chase Weidmann, PhD (Department of Chemistry)

Weidmann, C.A., et al. Analysis of RNA–protein networks with RNP-MaP defines functional hubs on RNA. Published Oct. 2020 in Nature Biotechnology (https://doi.org/10.1038/s41587-020-0709-7)

2020

Guy Aaron Hobbs, PhD (Department of Biochemistry & Biophysics)

Hobbs, G.A., et al. Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer. Published Oct. 2019 in Cancer Discovery (https://doi.org/10.1158/2159-8290.CD-19-1006)

Daniel Hollern, PhD (Department of Genetics)

Hollern, D.P, et al. B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer. Published Nov. 2019 in Cell (https://doi.org/10.1016/j.cell.2019.10.028)

Frances Potjewyd, PhD (Division of Chemical Biology and Medicinal Chemistry – Eshelman School of Pharmacy)

Potjewyd, F. M., et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Published Dec. 2019 in Cell Chemical Biology (https://doi.org/10.1016/j.chembiol.2019.11.006)

2019

Kirsten Bryant, PhD (Department of Pharmacology)

Bryant, K.L., et al. Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer. Published Mar. 2019 in Nature Medicine (https://doi.org/10.1038/s41591-019-0368-8)

Ariel “Ari” Pani, PhD (Department of Biology)

Pani, A.M., & Goldstein, B. Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal. Published Aug. 2018 in eLife (https://doi.org/10.7554/eLife.38325.001)

John Pryor, PhD (Department of Biochemistry & Biophysics)

Pryor, J.M., et al. Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining. Published Sep. 2018 in Science (https://doi.org/10.1126/science.aat2477)

2018

Thomas Boothby, PhD (Department of Chemistry)

Boothby, T., et al. Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation. Published Mar. 2017 in Molecular Cell (https://doi.org/10.1016/j.molcel.2017.02.018)

Hui Feng, PhD (Department of Medicine)

Feng, H., et al. NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR. Published Oct. 2017 in Nature Immunology (https://doi.org/10.1038/ni.3853)

Jenna Honeycutt, PhD (Division of Infectious Diseases)

Honeycutt, J., et al. HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy. Published Apr. 2017 in Nature Medicine (https://doi.org/10.1038/nm.4319)